HitPredict

Interactor 1: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Interactor 2: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.947

Property	Details
Experiments	11805826, 16554755, 16429126, 17499717, 37968396, 31848235
Identification Methods	tandem affinity purification, affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	JAB~VWA_2
Common GO terms	GO:0000502 - proteasome complex GO:0006511 - ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 268 Sc			1 338
+	Dm
		684545 PSMD4_DROME (1-256): 5.77e-113: 332: 41.80		PSMD7_DROME (4-325): 8.26e-103: 307: 45.68
+	Hs
		906487 PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15		PSMD7_HUMAN (6-301): 2.64e-97: 292: 50.51
+	Sp
		314152 RPN10_SCHPO (1-261): 5.82e-112: 323: 45.59		RPN11_SCHPO (1-263): 3.36e-61: 199: 19.11
+	Hs
		138035 PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15		PSDE_HUMAN (6-142): 4.76e-27: 109: 24.65
+	Hs
		138162 Q5VWC4_HUMAN (1-236): 7.78e-119: 346: 49.15		PSDE_HUMAN (6-142): 4.76e-27: 109: 24.65