Protein: PSB2
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)

Gene: PSB2, PSMB2
Organism: Homo sapiens
Interactions: 190
UniProt ID: P49721

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637649

PSA2
Proteasome subunit alpha type-2

8

20

Small-scale

0.972

High

637360

PSA1
Proteasome subunit alpha type-1

9

20

Small-scale

0.970

High

831958

PSB3
Proteasome subunit beta type-3

7

20

Small-scale

0.967

High

832151

PSB7
Proteasome subunit beta type-7

6

19

Small-scale

0.938

High

832181

POMP
Proteasome maturation protein

5

15

Small-scale

0.932

High

594479

PSB1
Proteasome subunit beta type-1

5

20

Small-scale

0.930

High

832092

PSME1
Proteasome activator complex subunit 1

5

20

Small-scale

0.925

High

156252

PSA7
Proteasome subunit alpha type-7

5

20

Small-scale

0.922

High

832080

PSA6
Proteasome subunit alpha type-6

5

20

Small-scale

0.922

High

656681

PSB5
Proteasome subunit beta type-5

5

19

Small-scale

0.919

High

638086

PSA4
Proteasome subunit alpha type-4

5

20

Small-scale

0.919

High

656430

PSB4
Proteasome subunit beta type-4

5

20

Small-scale

0.919

High

656570

PSB6
Proteasome subunit beta type-6

5

19

Small-scale

0.919

High

656099

PSB9
Proteasome subunit beta type-9

4

20

High-throughput

0.903

High

121708

PSD11
26S proteasome non-ATPase regulatory subunit 11

4

20

Small-scale

0.900

High

656174

PSA5
Proteasome subunit alpha type-5

4

20

Small-scale

0.900

High

832103

PSME4
Proteasome activator complex subunit 4

4

11

Small-scale

0.900

High

832175

PSME2
Proteasome activator complex subunit 2

4

20

Small-scale

0.892

High

637812

PSA3
Proteasome subunit alpha type-3

3

20

Small-scale

0.855

High

730215

PRS7
26S proteasome regulatory subunit 7

3

20

Small-scale

0.839

High

798614

PRS6B
26S proteasome regulatory subunit 6B

2

20

Small-scale

0.776

High

832083

PRS4
26S proteasome regulatory subunit 4

2

20

Small-scale

0.776

High

832084

PRS8
26S proteasome regulatory subunit 8

2

20

Small-scale

0.776

High

832086

PRS10
26S proteasome regulatory subunit 10B

2

20

Small-scale

0.776

High

832070

PSB2
Proteasome subunit beta type-2

2

19

Small-scale

0.755

High

572895

PRS6A
26S proteasome regulatory subunit 6A

2

20

Small-scale

0.737

High

130798

PSDE
26S proteasome non-ATPase regulatory subunit 14

5

20

Small-scale

0.699

High

832184

FBX7
F-box only protein 7

4

6

Small-scale

0.694

High

832138

PSMA8
Proteasome subunit alpha-type 8

1

20

High-throughput

0.691

High

832188

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

4

18

Small-scale

0.691

High

832091

UBE3A
Ubiquitin-protein ligase E3A

4

17

Small-scale

0.676

High

314746

PSMG1
Proteasome assembly chaperone 1

3

5

High-throughput

0.675

High

832116

AKIR2
Akirin-2

3

8

Small-scale

0.667

High

832078

PSMD4
26S proteasome non-ATPase regulatory subunit 4

3

14

Small-scale

0.650

High

832152

PSMD1
26S proteasome non-ATPase regulatory subunit 1

3

20

Small-scale

0.633

High

832146

PSMF1
Proteasome inhibitor PI31 subunit

2

4

High-throughput

0.628

High

832147

PSMG2
Proteasome assembly chaperone 2

2

11

High-throughput

0.628

High

791380

HD
Huntingtin

2

5

High-throughput

0.621

High

832143

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

2

9

Small-scale

0.611

High

832174

AMFR
E3 ubiquitin-protein ligase AMFR

2

16

High-throughput

0.611

High

832093

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

832113

KR197
Keratin-associated protein 19-7

2

1

High-throughput

0.606

High

832131

KR191
Keratin-associated protein 19-1

2

1

High-throughput

0.606

High

832182

AXIN2
Axin-2

2

1

High-throughput

0.606

High

121967

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

20

Small-scale

0.601

High

581547

VCAM1
Vascular cell adhesion protein 1

2

4

High-throughput

0.601

High

832087

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

20

Small-scale

0.601

High

832095

PSMD2
26S proteasome non-ATPase regulatory subunit 2

2

20

Small-scale

0.601

High

832104

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

20

Small-scale

0.601

High

832179

PSD13
26S proteasome non-ATPase regulatory subunit 13

2

13

Small-scale

0.601

High

226856

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.584

High

475487

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

Small-scale

0.584

High

503682

HSP7C
Heat shock cognate 71 kDa protein

2

8

Small-scale

0.584

High

779019

CCNF
Cyclin-F

2

5

High-throughput

0.584

High

832075

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

2

11

Small-scale

0.584

High

832076

RD23A
UV excision repair protein RAD23 homolog A

2

20

Small-scale

0.584

High

832077

RD23B
UV excision repair protein RAD23 homolog B

2

20

Small-scale

0.584

High

832122

ECM29
Proteasome adapter and scaffold protein ECM29

2

11

Small-scale

0.584

High

832173

UBQL2
Ubiquilin-2

2

20

Small-scale

0.584

High

832111

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.580

High

832112

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.580

High

92611

E9PMD8
Proteasome 26S subunit, ATPase 3

1

20

High-throughput

0.575

High

108934

H0YKT8
Proteasome subunit beta

1

19

High-throughput

0.575

High

832082

PSME3
Proteasome activator complex subunit 3

1

20

Small-scale

0.575

High

369191

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

832109

ADRM1
Proteasomal ubiquitin receptor ADRM1

2

10

Small-scale

0.571

High

832118

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

6

High-throughput

0.571

High

496565

TAU
Microtubule-associated protein tau

2

6

High-throughput

0.552

High

202607

TXNL1
Thioredoxin-like protein 1

2

0

Small-scale

0.547

High

388305

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

198576

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

10

High-throughput

0.536

High

362944

FINC
Fibronectin

1

3

High-throughput

0.536

High

528773

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.536

High

832072

PSN1
Presenilin-1

1

4

High-throughput

0.536

High

832089

SKP1
S-phase kinase-associated protein 1

1

9

High-throughput

0.536

High

832106

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

14

High-throughput

0.536

High

832107

UBE3C
Ubiquitin-protein ligase E3C

1

20

High-throughput

0.536

High

832129

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

20

High-throughput

0.536

High

832133

CDK20
Cyclin-dependent kinase 20

1

5

High-throughput

0.536

High

832136

ARRD4
Arrestin domain-containing protein 4

1

8

High-throughput

0.536

High

832154

SLX1
Structure-specific endonuclease subunit SLX1

1

4

High-throughput

0.536

High

832166

ANKZ1
tRNA endonuclease ANKZF1

1

1

High-throughput

0.536

High

832185

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

6

High-throughput

0.536

High

576050

GPX2
Glutathione peroxidase 2

1

0

High-throughput

0.518

High

832189

DDX49
Probable ATP-dependent RNA helicase DDX49

1

0

High-throughput

0.518

High

171486

UBD
Ubiquitin D

1

20

Small-scale

0.501

High

316825

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.500

High

832099

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.500

High

832156

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.500

High

506296

MBL2
Mannose-binding protein C

1

3

High-throughput

0.489

High

531457

K1C13
Keratin, type I cytoskeletal 13

1

6

High-throughput

0.481

High

174720

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

Small-scale

0.479

High

213503

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

4

Small-scale

0.479

High

244115

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

255593

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.479

High

294533

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

298280

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

304070

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

Small-scale

0.479

High

346234

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

349975

RASK
GTPase KRas

1

1

High-throughput

0.479

High

397842

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.479

High

487231

ANDR
Androgen receptor

1

6

High-throughput

0.479

High

509552

UBL4A
Ubiquitin-like protein 4A

1

20

Small-scale

0.479

High

530509

ITA4
Integrin alpha-4

1

2

High-throughput

0.479

High

552226

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

564036

HSP76
Heat shock 70 kDa protein 6

1

10

Small-scale

0.479

High

570500

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

7

High-throughput

0.479

High

650665

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

719963

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

801828

RECQ1
ATP-dependent DNA helicase Q1

1

9

High-throughput

0.479

High

803436

BAG6
Large proline-rich protein BAG6

1

20

Small-scale

0.479

High

807635

MAP1B
Microtubule-associated protein 1B

1

7

High-throughput

0.479

High

832071

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

832074

ATX3
Ataxin-3

1

4

High-throughput

0.479

High

832081

UBC12
NEDD8-conjugating enzyme Ubc12

1

11

High-throughput

0.479

High

832085

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

11

High-throughput

0.479

High

832090

PO5F1
POU domain, class 5, transcription factor 1

1

2

High-throughput

0.479

High

832094

NFX1
Transcriptional repressor NF-X1

1

4

High-throughput

0.479

High

832096

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

832097

SQSTM
Sequestosome-1

1

3

Small-scale

0.479

High

832098

CUL3
Cullin-3

1

5

High-throughput

0.479

High

832101

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

6

Small-scale

0.479

High

832105

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

832110

MK06
Mitogen-activated protein kinase 6

1

3

High-throughput

0.479

High

832114

LARP7
La-related protein 7

1

7

High-throughput

0.479

High

832115

MIDN
Midnolin

1

6

High-throughput

0.479

High

832119

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

Small-scale

0.479

High

832120

DDI2
Protein DDI1 homolog 2

1

20

High-throughput

0.479

High

832123

VIR
Protein virilizer homolog

1

6

High-throughput

0.479

High

832124

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

832126

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

832128

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

832130

GOLI
E3 ubiquitin-protein ligase RNF130

1

20

High-throughput

0.479

High

832137

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

832140

RBCC1
RB1-inducible coiled-coil protein 1

1

3

High-throughput

0.479

High

832142

RN138
E3 ubiquitin-protein ligase RNF138

1

7

Small-scale

0.479

High

832144

ASB11
Ankyrin repeat and SOCS box protein 11

1

3

High-throughput

0.479

High

832145

SSH1
Protein phosphatase Slingshot homolog 1

1

3

High-throughput

0.479

High

832148

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.479

High

832149

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

6

Small-scale

0.479

High

832150

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

832153

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

832155

RN126
E3 ubiquitin-protein ligase RNF126

1

7

Small-scale

0.479

High

832158

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

6

Small-scale

0.479

High

832159

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

12

High-throughput

0.479

High

832160

PIP30
PSME3-interacting protein

1

2

Small-scale

0.479

High

832161

SHRPN
Sharpin

1

1

Small-scale

0.479

High

832163

Q9H4D1
Protein kinase

1

2

High-throughput

0.479

High

832164

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

832165

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

2

High-throughput

0.479

High

832167

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.479

High

832168

BIRC6
Baculoviral IAP repeat-containing protein 6

1

14

Small-scale

0.479

High

832170

RN181
E3 ubiquitin-protein ligase RNF181

1

8

Small-scale

0.479

High

832171

HDAC6
Histone deacetylase 6

1

4

Small-scale

0.479

High

832172

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

832176

FZR1
Fizzy-related protein homolog

1

11

High-throughput

0.479

High

832177

UBQL1
Ubiquilin-1

1

20

High-throughput

0.479

High

832178

CHIP
E3 ubiquitin-protein ligase CHIP

1

5

Small-scale

0.479

High

832180

NSF1C
NSFL1 cofactor p47

1

1

Small-scale

0.479

High

832186

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

Small-scale

0.479

High

832187

TRAF6
TNF receptor-associated factor 6

1

8

High-throughput

0.479

High

49560

A1A4E9
Keratin 13

1

6

High-throughput

0.470

High

210892

GET3
ATPase GET3

1

0

Small-scale

0.458

High

602959

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

0

High-throughput

0.458

High

832108

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

832132

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

832139

HM13
Minor histocompatibility antigen H13

1

0

Small-scale

0.458

High

695

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

20

High-throughput

0.445

High

483753

HS71A
Heat shock 70 kDa protein 1A

1

10

Small-scale

0.445

High

483783

HS71B
Heat shock 70 kDa protein 1B

1

10

Small-scale

0.445

High

819778

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

7

Small-scale

0.445

High

832073

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

20

Small-scale

0.445

High

832079

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

832088

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

18

Small-scale

0.445

High

832100

DAG1
Dystroglycan 1

1

1

Small-scale

0.445

High

832121

Q5VWC4
26S proteasome non-ATPase regulatory subunit 4

1

14

High-throughput

0.445

High

832162

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

832169

SPHK1
Sphingosine kinase 1

1

1

Small-scale

0.445

High

329499

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.437

High

832102

GRM2
Metabotropic glutamate receptor 2

1

6

High-throughput

0.437

High

832117

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

20

High-throughput

0.437

High

832125

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

832134

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.437

High

832141

DDI1
Protein DDI1 homolog 1

1

20

High-throughput

0.437

High

832183

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

832157

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

831099

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

832135

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

832127

KCTD9
BTB/POZ domain-containing protein KCTD9

1

0

High-throughput

0.299

High


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Last updated: 15 Jul 2024