HitPredict

Interactor 1: MAP1B (P46821)
Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]
Gene: MAP1B

Interactor 2: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2468 Hs			1 393
+	Hs
		734886 MAP1B_HUMAN (1-2468): 0: 950: 100.00		MP2K2_HUMAN (1-391): 2.96e-123: 363: 79.40
+	Hs
		807687 MAP1B_HUMAN (1-2468): 0: 950: 100.00		CDK3_HUMAN (65-379): 5.96e-120: 351: 21.81
+	Hs
		807705 MAP1B_HUMAN (1-2468): 0: 950: 100.00		STK4_HUMAN (37-369): 2.53e-111: 336: 30.06
+	Hs
		807708 MAP1B_HUMAN (1-2468): 0: 950: 100.00		STK3_HUMAN (50-369): 2.6e-109: 331: 33.23
+	Hs
		153100 MAP1B_HUMAN (1-2468): 0: 950: 100.00		MP2K7_HUMAN (35-375): 7.04e-61: 204: 35.49
+	Hs
		626102 APC_HUMAN (603-2214): 4.09e-44: 180: 9.80		MP2K1_HUMAN (1-393): 1.26e-125: 369: 100.00
+	Hs
		1023059 MAP1S_HUMAN (1859-2468): 1.33e-37: 157: 16.39		STK4_HUMAN (37-369): 2.53e-111: 336: 30.06
+	Hs
		1027383 MAP1S_HUMAN (1859-2468): 1.33e-37: 157: 16.39		STK3_HUMAN (50-369): 2.6e-109: 331: 33.23
+	Hs
		625662 NCOR2_HUMAN (334-2072): 6.72e-15: 83.7: 6.77		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		682094 NCOR2_HUMAN (334-2072): 6.72e-15: 83.7: 6.77		AKT1_HUMAN (39-389): 1.97e-120: 359: 19.44
+	Hs
		625528 TITIN_HUMAN (362-1320): 1.1e-10: 69.8: 8.51		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27