Protein: CTK1
CTD kinase subunit alpha (CTDK-I subunit alpha) (EC 2.7.11.23) (CTD kinase 58 kDa subunit) (CTD kinase subunit 1)

Gene: CTK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: Q03957

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

863298

CTK2
CTD kinase subunit beta

13

20

Small-scale

0.980

High

676769

GBP2
Serine/arginine

6

7

Small-scale

0.942

High

863309

CTK3
CTD kinase subunit gamma

11

0

Small-scale

0.925

High

807692

HRB1
Serine/arginine

3

6

Small-scale

0.867

High

1031045

NOP3
Serine/arginine

3

20

Small-scale

0.861

High

448794

SNF1
Carbon catabolite-derepressing protein kinase

1

3

Small-scale

0.752

High

402106

RPB1
DNA-directed RNA polymerase II subunit RPB1

7

11

Small-scale

0.743

High

1044571

YRA1
RNA annealing protein YRA1

1

9

Small-scale

0.692

High

438224

CDC37
Hsp90 co-chaperone Cdc37

1

11

High-throughput

0.691

High

849785

CAK1
Serine/threonine-protein kinase CAK1

1

17

Small-scale

0.647

High

403645

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

9

High-throughput

0.646

High

381243

H2B1
Histone H2B.1

2

10

Small-scale

0.624

High

742938

HSP79
Heat shock protein homolog SSE2

2

18

High-throughput

0.621

High

646525

RAD53
Serine/threonine-protein kinase RAD53

1

14

High-throughput

0.618

High

1044570

NCBP2
Nuclear cap-binding protein subunit 2

1

5

Small-scale

0.618

High

865611

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.614

High

925348

CRZ1
Transcriptional regulator CRZ1

1

0

High-throughput

0.614

High

149941

RS9A
Small ribosomal subunit protein uS4A

2

5

High-throughput

0.611

High

436154

RS13
Small ribosomal subunit protein uS15

2

3

High-throughput

0.611

High

674819

RS2
Small ribosomal subunit protein uS5

2

3

Small-scale

0.595

High

645523

XRN1
5'-3' exoribonuclease 1

2

2

Small-scale

0.594

High

676975

SRO9
RNA-binding protein SRO9

2

14

Small-scale

0.594

High

893219

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

2

2

Small-scale

0.571

High

419496

H2A1
Histone H2A.1

1

8

Small-scale

0.561

High

419858

H2A2
Histone H2A.2

1

8

Small-scale

0.561

High

546138

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.552

High

637275

PWP1
Periodic tryptophan protein 1

1

12

High-throughput

0.541

High

382314

H4
Histone H4

1

5

High-throughput

0.536

High

525035

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.536

High

633507

PP11
Serine/threonine-protein phosphatase PP1-1

1

12

High-throughput

0.536

High

747561

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.521

High

753568

RS3A1
Small ribosomal subunit protein eS1A

2

4

High-throughput

0.521

High

1044567

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.518

High

736526

SFP1
Transcription factor SFP1

1

0

High-throughput

0.513

High

918811

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.513

High

924620

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

561331

DPOLA
DNA polymerase alpha catalytic subunit A

1

5

Small-scale

0.512

High

381621

H2B2
Histone H2B.2

1

10

Small-scale

0.501

High

464339

OAT
Ornithine aminotransferase

1

1

High-throughput

0.501

High

811155

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.501

High

818391

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

1

High-throughput

0.501

High

845898

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

2

High-throughput

0.501

High

1044572

H2AZ
Histone H2A.Z

1

10

High-throughput

0.501

High

531395

METK1
S-adenosylmethionine synthase 1

1

2

High-throughput

0.500

High

590713

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

621404

METK2
S-adenosylmethionine synthase 2

1

2

High-throughput

0.500

High

680029

CDC48
Cell division control protein 48

1

4

High-throughput

0.500

High

585147

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.480

High

624468

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.480

High

763547

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.480

High

781521

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.480

High

849926

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

863203

SIP4
Protein SIP4

1

0

High-throughput

0.480

High

1044566

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.480

High

394876

EF1A
Elongation factor 1-alpha

1

6

Small-scale

0.479

High

512632

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

514820

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.479

High

594551

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

598911

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

8

High-throughput

0.479

High

661191

SPT6
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

677544

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

689644

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

778518

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.479

High

792229

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.479

High

802373

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

826798

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

874511

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

1033545

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

1033881

PRS8
26S proteasome regulatory subunit 8 homolog

1

8

Small-scale

0.479

High

1044568

SUB2
ATP-dependent RNA helicase SUB2

1

14

Small-scale

0.479

High

605925

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

757532

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.458

High

1044565

ARA2
D-arabinose 1-dehydrogenase

1

3

High-throughput

0.457

High

368744

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.457

High

835883

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.445

High

885079

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.445

High

94587

STE2
Pheromone alpha factor receptor

1

1

High-throughput

0.439

High

383880

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.437

High

410321

RL25
Large ribosomal subunit protein uL23

1

5

High-throughput

0.437

High

433834

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

455245

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

503222

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504399

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

511282

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.437

High

513202

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

513568

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.437

High

919483

CRH1
Congo red hypersensitive protein 1 [Includes: Chitinase CRH1

1

2

High-throughput

0.437

High

1044569

RS10A
Small ribosomal subunit protein eS10A

1

6

High-throughput

0.437

High

858396

STU2
Protein STU2

1

5

High-throughput

0.417

High

712662

RL8B
Large ribosomal subunit protein eL8B

1

6

High-throughput

0.407

High

678208

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.279

Low

918254

YG1D
Probable transcriptional regulatory protein HAH1

1

0

High-throughput

0.261

Low

1039094

YP077
Uncharacterized protein YPL077C

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025