Interactor 1: MAP1B (P46821)
Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]
Gene: MAP1B

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.679

The method score is based on:

Property Details
Experiments 21159966, unassigned1853, 24754922
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, two hybrid, protein kinase assay, pull down
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008017 - microtubule binding
GO:0030424 - axon
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2468
Hs

1 2527
+ Hs
+ Hs
+ Hs
+ Zm
+ Dm
+ Zm

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Last updated: 15 Jul 2024