Protein: ATC2
Calcium-transporting ATPase 2 (EC 7.2.2.10) (Vacuolar Ca(2+)-ATPase)

Gene: ATC2, PMC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P38929

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005388 - P-type calcium transporter activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006816 - calcium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

807723

ATC2
Calcium-transporting ATPase 2

2

15

High-throughput

0.730

High

807748

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

3

0

High-throughput

0.625

High

740056

VPP1
V-type proton ATPase subunit a, vacuolar isoform

2

2

Small-scale

0.614

High

807750

SNA4
Protein SNA4

2

1

High-throughput

0.613

High

736181

YBT1
ATP-dependent bile acid permease

2

5

High-throughput

0.608

High

743682

VATD
V-type proton ATPase subunit D

2

1

High-throughput

0.608

High

757376

VPS35
Vacuolar protein sorting-associated protein 35

2

1

High-throughput

0.608

High

807754

NYV1
Vacuolar v-SNARE NYV1

2

9

Small-scale

0.601

High

564729

ATC1
Calcium-transporting ATPase 1

1

15

High-throughput

0.590

High

807738

MEH1
Protein MEH1

2

0

High-throughput

0.587

High

797834

FTH1
Iron transporter FTH1

2

0

High-throughput

0.582

High

807726

VATH
V-type proton ATPase subunit H

2

0

High-throughput

0.582

High

807734

RAGCD
GTP-binding protein GTR2

2

0

High-throughput

0.582

High

807752

TMS1
Membrane protein TMS1

2

0

High-throughput

0.582

High

737223

HXT1
Low-affinity glucose transporter HXT1

1

3

High-throughput

0.541

High

745209

COT1
Vacuolar zinc transporter COT1

1

3

High-throughput

0.541

High

793377

AGP2
General amino acid permease AGP2

1

2

High-throughput

0.541

High

807724

VATF
V-type proton ATPase subunit F

1

1

High-throughput

0.541

High

807725

VAC8
Vacuolar protein 8

1

2

High-throughput

0.541

High

807739

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

5

High-throughput

0.541

High

807753

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

5

High-throughput

0.541

High

806224

CTR2
Copper transport protein CTR2

1

0

High-throughput

0.518

High

807743

FMP42
Protein FMP42

1

0

High-throughput

0.518

High

807746

DPP1
Diacylglycerol pyrophosphate phosphatase 1

1

0

High-throughput

0.518

High

807751

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.518

High

807727

MDJ2
Mitochondrial DnaJ homolog 2

1

1

High-throughput

0.494

High

807730

ATG27
Autophagy-related protein 27

1

1

High-throughput

0.494

High

807741

VBA4
Vacuolar basic amino acid transporter 4

1

2

High-throughput

0.481

High

510483

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

579375

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

679670

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

709749

BMH1
Protein BMH1

1

6

High-throughput

0.479

High

795337

ATG8
Autophagy-related protein 8

1

3

High-throughput

0.479

High

807731

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

804795

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

807732

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

526681

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

791961

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.438

High

807729

EMP47
Protein EMP47

1

0

High-throughput

0.438

High

807737

PMP3
Plasma membrane proteolipid 3

1

0

High-throughput

0.438

High

807755

MAM3
Protein MAM3

1

0

High-throughput

0.438

High

430848

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

2

High-throughput

0.437

High

694546

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.437

High

807736

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

528585

CP51
Lanosterol 14-alpha demethylase CYP51

1

3

High-throughput

0.417

High

777207

KES1
Oxysterol-binding protein homolog 4

1

3

High-throughput

0.417

High

802934

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.417

High

807742

RTN1
Reticulon-like protein 1

1

4

High-throughput

0.417

High

807744

ERP1
Protein ERP1

1

4

High-throughput

0.417

High

807749

MRL1
Mannose 6-phosphate receptor-like protein 1

2

0

High-throughput

0.295

High

794778

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.282

High

807740

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.282

High

807745

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.279

Low

802822

GRE3
NADPH-dependent aldose reductase GRE3

1

0

High-throughput

0.269

Low

807728

SET4
SET domain-containing protein 4

1

0

Small-scale

0.249

Low

807733

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

807747

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

807735

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.238

Low

807756

COX26
Cytochrome c oxidase subunit 26, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025