HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: TMM51 (Q9NW97)
Transmembrane protein 51
Gene: TMEM51

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.636

Property	Details
Experiments	26186194, 28514442, 33961781, 37219487
Identification Methods	affinity chromatography technology, unspecified method, phage display, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1319 Hs			1 253
+	Hs
		1299648 NED4L_HUMAN (517-1319): 0: 934: 62.26		TMM51_HUMAN (1-253): 4.38e-174: 481: 100.00
+	Hs
		1327923 WWP1_HUMAN (389-800): 7.48e-49: 191: 17.86		TMM51_HUMAN (1-253): 4.38e-174: 481: 100.00
+	Hs
		125753 WWP2_HUMAN (461-817): 1.56e-41: 167: 17.91		TMM51_HUMAN (1-253): 4.38e-174: 481: 100.00
+	Hs
		1294872 ITCH_HUMAN (468-799): 2.73e-28: 125: 19.42		TMM51_HUMAN (1-253): 4.38e-174: 481: 100.00
+	Hs
		1347135 HECW2_HUMAN (434-992): 3.07e-10: 67.1: 13.83		TMM51_HUMAN (1-253): 4.38e-174: 481: 100.00