Protein: K2C75
Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18)

Gene: K2C75, KRT75
Organism: Homo sapiens
Interactions: 170
UniProt ID: O95678

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005882 - intermediate filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

280503

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.794

High

280765

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

280840

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.783

High

280938

KRT38
Keratin, type I cuticular Ha8

2

20

High-throughput

0.783

High

318768

VIME
Vimentin

2

20

High-throughput

0.783

High

318769

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

318771

K2C3
Keratin, type II cytoskeletal 3

2

13

High-throughput

0.783

High

318773

K1C13
Keratin, type I cytoskeletal 13

2

20

High-throughput

0.783

High

318775

DESM
Desmin

2

20

High-throughput

0.783

High

318776

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.783

High

318780

K1C20
Keratin, type I cytoskeletal 20

2

20

High-throughput

0.783

High

318786

PERI
Peripherin

2

20

High-throughput

0.783

High

318795

K22O
Keratin, type II cytoskeletal 2 oral

2

19

High-throughput

0.783

High

318807

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

318810

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

318814

K1C24
Keratin, type I cytoskeletal 24

2

20

High-throughput

0.783

High

318825

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.783

High

318830

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

318831

K1C26
Keratin, type I cytoskeletal 26

2

20

High-throughput

0.783

High

318832

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

318856

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

318896

WWOX
WW domain-containing oxidoreductase

3

1

High-throughput

0.653

High

318765

K2C75
Keratin, type II cytoskeletal 75

1

12

High-throughput

0.621

High

318770

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.621

High

318808

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.621

High

154914

NDC80
Kinetochore protein NDC80 homolog

2

20

High-throughput

0.606

High

159824

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

5

High-throughput

0.606

High

169758

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.606

High

207863

XPOT
Exportin-T

2

5

High-throughput

0.606

High

259908

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

1

High-throughput

0.606

High

307934

ZWINT
ZW10 interactor

2

1

High-throughput

0.606

High

318767

SPTA1
Spectrin alpha chain, erythrocytic 1

2

4

High-throughput

0.606

High

318774

TRI27
Zinc finger protein RFP

2

5

High-throughput

0.606

High

318785

TXLNA
Alpha-taxilin

2

17

High-throughput

0.606

High

318790

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

4

High-throughput

0.606

High

318801

TRAF1
TNF receptor-associated factor 1

2

8

High-throughput

0.606

High

318812

CDC37
Hsp90 co-chaperone Cdc37

2

1

High-throughput

0.606

High

318813

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

8

High-throughput

0.606

High

318819

PKHG4
Puratrophin-1

2

2

High-throughput

0.606

High

318835

CEP57
Centrosomal protein of 57 kDa

2

4

High-throughput

0.606

High

318847

CCHCR
Coiled-coil alpha-helical rod protein 1

2

1

High-throughput

0.606

High

318853

ASB15
Ankyrin repeat and SOCS box protein 15

2

10

High-throughput

0.606

High

318860

MGN2
Protein mago nashi homolog 2

2

1

High-throughput

0.606

High

318861

FBX17
F-box only protein 17

2

1

High-throughput

0.606

High

318867

KCTD7
BTB/POZ domain-containing protein KCTD7

2

1

High-throughput

0.606

High

318869

SPAG5
Sperm-associated antigen 5

2

8

High-throughput

0.606

High

318873

TCHP
Trichoplein keratin filament-binding protein

2

5

High-throughput

0.606

High

318875

KIFC3
Kinesin-like protein KIFC3

2

9

High-throughput

0.606

High

318885

CARD9
Caspase recruitment domain-containing protein 9

2

3

High-throughput

0.606

High

318891

NEK6
Serine/threonine-protein kinase Nek6

2

4

High-throughput

0.606

High

318894

AIRIM
AFG2-interacting ribosome maturation factor

2

1

High-throughput

0.606

High

318895

ABI2
Abl interactor 2

2

14

High-throughput

0.606

High

318903

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

20

High-throughput

0.606

High

318906

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

2

High-throughput

0.606

High

318789

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

0

High-throughput

0.580

High

318836

GLCTK
Glycerate kinase

2

0

High-throughput

0.580

High

318844

MNS1
Meiosis-specific nuclear structural protein 1

2

0

High-throughput

0.580

High

318862

DTBP1
Dysbindin

2

0

High-throughput

0.580

High

318871

TS101
Tumor susceptibility gene 101 protein

2

0

High-throughput

0.580

High

318874

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.580

High

318892

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

318898

RCOR3
REST corepressor 3

2

0

High-throughput

0.580

High

318899

NCDN
Neurochondrin

2

0

High-throughput

0.580

High

318900

CPNE7
Copine-7

2

0

High-throughput

0.580

High

318905

SUFU
Suppressor of fused homolog

2

0

High-throughput

0.580

High

318908

NDK7
Nucleoside diphosphate kinase homolog 7

2

0

High-throughput

0.580

High

318783

NUP62
Nuclear pore glycoprotein p62

2

4

High-throughput

0.561

High

318902

RSP14
Radial spoke head 14 homolog

2

4

High-throughput

0.561

High

62256

GG6L9
Golgin subfamily A member 6-like protein 9

2

8

High-throughput

0.553

High

155504

TNPO2
Transportin-2

2

1

High-throughput

0.553

High

204266

MS18B
Protein Mis18-beta

2

5

High-throughput

0.553

High

314502

LCA5L
Lebercilin-like protein

2

5

High-throughput

0.553

High

318766

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

10

High-throughput

0.553

High

318777

RBTN2
Rhombotin-2

2

7

High-throughput

0.553

High

318778

RBTN1
Rhombotin-1

2

7

High-throughput

0.553

High

318781

TRI23
E3 ubiquitin-protein ligase TRIM23

2

5

High-throughput

0.553

High

318782

ZNF76
Zinc finger protein 76

2

2

High-throughput

0.553

High

318793

LMO4
LIM domain transcription factor LMO4

2

7

High-throughput

0.553

High

318796

CDK18
Cyclin-dependent kinase 18

2

1

High-throughput

0.553

High

318797

GOGA2
Golgin subfamily A member 2

2

5

High-throughput

0.553

High

318798

INCA1
Protein INCA1

2

1

High-throughput

0.553

High

318800

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

1

High-throughput

0.553

High

318820

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

9

High-throughput

0.553

High

318823

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

4

High-throughput

0.553

High

318824

C102B
Coiled-coil domain-containing protein 102B

2

2

High-throughput

0.553

High

318829

EPMIP
EPM2A-interacting protein 1

2

1

High-throughput

0.553

High

318833

TBCD1
TBC1 domain family member 1

2

2

High-throughput

0.553

High

318837

CF206
Cilia- and flagella-associated protein 206

2

1

High-throughput

0.553

High

318839

TXLNB
Beta-taxilin

2

8

High-throughput

0.553

High

318840

USBP1
Harmonin-binding protein USHBP1

2

3

High-throughput

0.553

High

318841

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

5

High-throughput

0.553

High

318842

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

1

High-throughput

0.553

High

318845

IKBD
NF-kappa-B inhibitor delta

2

4

High-throughput

0.553

High

318846

CA216
UPF0500 protein C1orf216

2

1

High-throughput

0.553

High

318851

TEKT4
Tektin-4

2

2

High-throughput

0.553

High

318859

TEKT1
Tektin-1

2

2

High-throughput

0.553

High

318865

GMCL1
Germ cell-less protein-like 1

2

1

High-throughput

0.553

High

318877

CAR10
Caspase recruitment domain-containing protein 10

2

5

High-throughput

0.553

High

318879

BEX2
Protein BEX2

2

1

High-throughput

0.553

High

318880

TRI54
Tripartite motif-containing protein 54

2

20

High-throughput

0.553

High

318890

KIF9
Kinesin-like protein KIF9

2

3

High-throughput

0.553

High

318907

WASC3
WASH complex subunit 3

2

2

High-throughput

0.553

High

318909

TNPO3
Transportin-3

2

6

High-throughput

0.553

High

318791

EPIPL
Epiplakin

1

18

High-throughput

0.536

High

318802

CUL1
Cullin-1

1

20

High-throughput

0.536

High

318803

CUL2
Cullin-2

1

20

High-throughput

0.536

High

318804

CUL3
Cullin-3

1

20

High-throughput

0.536

High

318806

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

318809

NUMA1
Nuclear mitotic apparatus protein 1

1

6

High-throughput

0.536

High

318811

NEDD8
NEDD8

1

2

High-throughput

0.536

High

318828

CSN6
COP9 signalosome complex subunit 6

1

7

High-throughput

0.536

High

318834

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

318857

CSN5
COP9 signalosome complex subunit 5

1

12

High-throughput

0.536

High

318858

CUL5
Cullin-5

1

20

High-throughput

0.536

High

318863

DCNL1
DCN1-like protein 1

1

2

High-throughput

0.536

High

318886

GAN
Gigaxonin

1

5

High-throughput

0.536

High

318815

Q49AR9
ANKS1A protein

1

9

High-throughput

0.515

High

318870

SORT
Sortilin

1

0

High-throughput

0.513

High

318897

CXXC1
CXXC-type zinc finger protein 1

1

0

High-throughput

0.513

High

264804

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.489

High

318805

CUL4A
Cullin-4A

1

20

High-throughput

0.489

High

318850

NUDT8
Mitochondrial coenzyme A diphosphatase NUDT8

1

1

High-throughput

0.489

High

66254

WASH1
WASH complex subunit 1

1

2

High-throughput

0.481

High

318817

AMOT
Angiomotin

1

2

High-throughput

0.481

High

318854

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

13

High-throughput

0.481

High

226160

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

318772

CFTR
Cystic fibrosis transmembrane conductance regulator

1

14

High-throughput

0.479

High

318784

IF4A3
Eukaryotic initiation factor 4A-III

1

7

High-throughput

0.479

High

318787

EPS15
Epidermal growth factor receptor substrate 15

1

10

High-throughput

0.479

High

318788

YAP1
Transcriptional coactivator YAP1

1

16

High-throughput

0.479

High

318799

TFCP2
Alpha-globin transcription factor CP2

1

4

High-throughput

0.479

High

318816

LARP7
La-related protein 7

1

9

High-throughput

0.479

High

318884

RN208
RING finger protein 208

1

18

Small-scale

0.479

High

57662

A2BDD9
AMOT protein

1

1

High-throughput

0.470

High

318843

CC197
Uncharacterized protein CCDC197

1

1

High-throughput

0.470

High

318866

MY15B
Unconventional myosin-XVB

1

4

High-throughput

0.470

High

305879

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

318779

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.445

High

318792

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

318881

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.445

High

318883

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

318887

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

High-throughput

0.445

High

318889

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

302748

HEXI1
Protein HEXIM1

1

16

High-throughput

0.437

High

318826

PRP8
Pre-mRNA-processing-splicing factor 8

1

6

High-throughput

0.437

High

318827

MEPCE
7SK snRNA methylphosphate capping enzyme

1

9

High-throughput

0.437

High

318878

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

4

High-throughput

0.437

High

318882

DDX24
ATP-dependent RNA helicase DDX24

1

14

High-throughput

0.437

High

318855

ESR2
Estrogen receptor beta

1

10

High-throughput

0.407

High

195298

DHX15
ATP-dependent RNA helicase DHX15

2

0

High-throughput

0.316

High

214813

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

2

0

High-throughput

0.316

High

269382

STX11
Syntaxin-11

2

0

High-throughput

0.316

High

278364

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.316

High

318794

U2AF1
Splicing factor U2AF 35 kDa subunit

2

0

High-throughput

0.316

High

318818

CTSRT
Cation channel sperm-associated targeting subunit tau

2

0

High-throughput

0.316

High

318821

TJAP1
Tight junction-associated protein 1

2

0

High-throughput

0.316

High

318822

EFHC1
EF-hand domain-containing protein 1

2

0

High-throughput

0.316

High

318838

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.316

High

318848

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

318852

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.316

High

318864

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

318868

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.316

High

318872

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

0

High-throughput

0.316

High

318876

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.316

High

318888

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

318901

CS025
UPF0449 protein C19orf25

2

0

High-throughput

0.316

High

318904

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

318893

ZC4H2
Zinc finger C4H2 domain-containing protein

1

0

High-throughput

0.279

Low

318849

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024