HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	31501420, 25796446, 30472188, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 535
+	Hs
		125363 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		125246 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		1306694 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		943497 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		125243 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		808395 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573490 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		573167 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		808391 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		943471 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Sc
		760677 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		TCPB_YEAST (9-532): 0: 566: 65.71
+	Sc
		792404 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		TCPH_YEAST (1-532): 0: 559: 33.09
+	Sc
		760801 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		TCPG_YEAST (5-528): 0: 537: 28.33
+	Hs
		1306711 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		943518 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		TCPB_HUMAN (1-535): 0: 586: 100.00