HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25796446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0010837 - regulation of keratinocyte proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 344
+	Hs
		125406 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		125425 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		125426 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		992947 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		992925 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		1028813 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		125430 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		125752 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		125122 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		125374 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		516643 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Sc
		765363 RSP5_YEAST (3-504): 1.79e-105: 334: 15.25		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Hs
		516402 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		808925 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PABP3_HUMAN (101-191): 1.24e-10: 64.5: 19.79
+	Hs
		952117 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		1028688 MAGI3_HUMAN (69-270): 5.85e-40: 156: 21.64		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Sc
		633986 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Sc
		965475 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Sc
		376913 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80
+	Hs
		516721 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79