HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: INADL (Q8NI35)
InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions)
Gene: PATJ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.747

Property	Details
Experiments	24366813, 25796446, 27684187, 30472188, 26933062, 38280479, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 1801
+	Hs
		125592 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		INADL_HUMAN (1-1801): 0: 1090: 100.00
+	Hs
		1246432 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		INADL_HUMAN (1-1801): 0: 1090: 100.00
+	Mm
		809075 YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70		INADL_MOUSE (1-1801): 0: 960: 77.88
+	Hs
		1246431 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		INADL_HUMAN (1-1801): 0: 1090: 100.00
+	Mm
		1144675 WWTR1_MOUSE (39-504): 9.89e-56: 193: 38.90		INADL_MOUSE (1-1801): 0: 960: 77.88
+	Hs
		1271021 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		DLG3_HUMAN (544-989): 6.06e-32: 137: 15.16
+	Mm
		93267 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG3_MOUSE (544-976): 3.73e-30: 132: 15.25
+	Mm
		808344 NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98		DLG3_MOUSE (544-976): 3.73e-30: 132: 15.25
+	Hs
		280032 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19
+	Hs
		808559 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PTN13_HUMAN (312-1336): 3.39e-25: 117: 12.43
+	Mm
		1143429 NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73		DLG4_MOUSE (503-837): 8.4e-23: 107: 16.47
+	Hs
		808565 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DLG1_HUMAN (565-1029): 2.84e-24: 113: 16.95
+	Mm
		93273 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG4_MOUSE (503-837): 8.4e-23: 107: 16.47
+	Hs
		1252467 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		LNX1_HUMAN (921-1318): 1.65e-21: 104: 16.67
+	Hs
		1299602 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		MAGI1_HUMAN (1-258): 2.32e-19: 97.8: 15.50
+	Hs
		808600 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SCRIB_HUMAN (142-438): 1.73e-10: 68.6: 26.78
+	Hs
		280067 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19
+	Hs
		1020213 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PTN13_HUMAN (312-1336): 3.39e-25: 117: 12.43
+	Hs
		1021560 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		DLG1_HUMAN (565-1029): 2.84e-24: 113: 16.95
+	Hs
		1050053 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SCRIB_HUMAN (142-438): 1.73e-10: 68.6: 26.78