HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	25796446, 27684187, 38280479, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 457
+	Hs
		125735 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		1336088 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		1327916 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		808283 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		1059444 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		ZN846_HUMAN (61-424): 9.09e-54: 190: 9.73
+	Hs
		808849 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		AJUBA_HUMAN (115-457): 1.26e-52: 187: 17.04
+	Hs
		200183 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Mm
		1143674 ITCH_MOUSE (2-504): 2.6e-119: 372: 14.36		TGFI1_MOUSE (43-397): 5.17e-34: 134: 16.62
+	Hs
		200184 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Hs
		200166 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Hs
		808847 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		200165 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Hs
		816282 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		LIMS1_HUMAN (298-452): 6.05e-14: 74.3: 24.54
+	Hs
		117260 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PDLI1_HUMAN (398-457): 9.72e-12: 68: 28.33
+	Hs
		808647 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		808640 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1274169 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		LPP_HUMAN (85-457): 5.09e-56: 197: 19.02
+	Hs
		1293394 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		1080775 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		1076525 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42