HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	24366813, 25796446, 27684187, 26933062, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 197
+	Hs
		125744 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Mm
		292484 YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70		LIN7C_MOUSE (1-197): 1.38e-57: 181: 100.00
+	Mm
		809071 YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70		SNTA1_MOUSE (40-184): 1.64e-30: 118: 26.71
+	Mm
		1143429 NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		125592 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Mm
		93273 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		808565 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1271021 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42
+	Mm
		93267 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73
+	Mm
		808344 NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73
+	Hs
		1252467 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		808559 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		280032 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MPDZ_HUMAN (39-162): 6.77e-13: 68.6: 20.16
+	Hs
		1299602 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44
+	Hs
		1246432 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Hs
		808858 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SNX27_HUMAN (91-175): 2.59e-12: 66.6: 38.14
+	Hs
		808786 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Hs
		1021560 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1020213 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		280067 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		MPDZ_HUMAN (39-162): 6.77e-13: 68.6: 20.16