HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38280479, 38223760
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0065003 - protein-containing complex assembly GO:1900182 - positive regulation of protein localization to nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 639
+	Hs
		1326808 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		125051 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		GRAP2_HUMAN (2-329): 1.68e-45: 166: 12.83
+	Hs
		125348 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		275221 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		GRAP2_HUMAN (2-329): 1.68e-45: 166: 12.83
+	Hs
		125507 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SH319_HUMAN (75-368): 3.05e-10: 65.4: 17.45
+	Hs
		557636 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		1049723 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARHG7_HUMAN (176-378): 4.79e-13: 74.6: 20.87
+	Hs
		1078893 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64
+	Hs
		808674 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SH319_HUMAN (75-368): 3.05e-10: 65.4: 17.45
+	Ce
		1341509 WWP1_CAEEL (98-504): 2.24e-109: 344: 15.89		Q9U2T9_CAEEL (27-492): 3.56e-11: 68.5: 13.89
+	Hs
		253399 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		SRGP2_HUMAN (2-443): 3.56e-43: 169: 11.52
+	Hs
		924608 Q1RLN5_HUMAN (5-284): 5.87e-38: 150: 17.54		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		51081 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SPD2B_HUMAN (3-589): 1.72e-16: 85.7: 11.64
+	Hs
		1126374 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SH319_HUMAN (75-368): 3.05e-10: 65.4: 17.45
+	Hs
		1256274 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		SH3R3_HUMAN (5-625): 1.58e-17: 88.8: 13.36