Protein: POP2
Poly(A) ribonuclease POP2 (EC 3.1.13.4) (CCR4-associated factor 1)

Gene: POP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P39008

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678958

NOT1
General negative regulator of transcription subunit 1

16

8

Small-scale

0.988

High

726212

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

21

13

Small-scale

0.769

High

809055

CAF40
Protein CAF40

12

5

Small-scale

0.760

High

761110

NOT4
General negative regulator of transcription subunit 4

9

3

Small-scale

0.748

High

438142

NOT2
General negative regulator of transcription subunit 2

5

10

Small-scale

0.710

High

438298

NOT3
General negative regulator of transcription subunit 3

4

6

Small-scale

0.693

High

809069

NOT5
General negative regulator of transcription subunit 5

4

6

Small-scale

0.672

High

809054

CF130
Protein CAF130

4

0

Small-scale

0.667

High

809040

MPT5
Suppressor protein MPT5

3

9

Small-scale

0.666

High

809042

DHH1
ATP-dependent RNA helicase DHH1

2

3

Small-scale

0.639

High

645925

DBF2
Cell cycle protein kinase DBF2

3

0

Small-scale

0.622

High

809063

MRB1
Methylated RNA-binding protein 1

2

6

Small-scale

0.600

High

521119

PRI1
DNA primase small subunit

2

0

High-throughput

0.595

High

632847

PRI2
DNA primase large subunit

2

0

High-throughput

0.595

High

793823

DPOA2
DNA polymerase alpha subunit B

2

0

High-throughput

0.595

High

672102

PUF4
Pumilio homology domain family member 4

2

9

Small-scale

0.595

High

776571

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.588

High

809046

NACB2
Nascent polypeptide-associated complex subunit beta-2

2

1

Small-scale

0.584

High

574577

YAK1
Dual specificity protein kinase YAK1

1

4

Small-scale

0.578

High

747850

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

526704

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

544884

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

809047

MOB1
DBF2 kinase activator protein MOB1

1

0

Small-scale

0.549

High

603467

VATA
V-type proton ATPase catalytic subunit A

2

1

High-throughput

0.537

High

721937

XPO1
Exportin-1

1

1

High-throughput

0.536

High

760650

WHI3
Protein WHI3

1

0

High-throughput

0.518

High

809056

NST1
Stress response protein NST1

1

0

High-throughput

0.518

High

809052

CTH2
mRNA decay factor CTH2

1

4

Small-scale

0.515

High

560699

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.513

High

809058

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

809059

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

Small-scale

0.508

High

403512

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

Small-scale

0.501

High

806456

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.493

High

809053

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.493

High

809070

DCP1
mRNA-decapping enzyme subunit 1

1

0

Small-scale

0.493

High

438844

CATT
Catalase T

1

0

High-throughput

0.486

High

809061

CSI1
Cop9 signalosome-interactor 1

1

0

High-throughput

0.486

High

809051

CTH1
mRNA decay factor CTH1

1

4

Small-scale

0.481

High

454575

TFS2
Transcription elongation factor S-II

1

0

Small-scale

0.480

High

585708

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

Small-scale

0.480

High

586459

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.480

High

632087

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.480

High

757322

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

Small-scale

0.480

High

809043

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

809045

RT106
Histone chaperone RTT106

1

0

Small-scale

0.480

High

721372

MCM4
DNA replication licensing factor MCM4

1

1

Small-scale

0.479

High

750659

PRS6A
26S proteasome regulatory subunit 6A

1

2

Small-scale

0.479

High

792808

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.479

High

809066

PUF3
mRNA-binding protein PUF3

1

9

Small-scale

0.479

High

809071

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

3

Small-scale

0.479

High

721613

RENT1
ATP-dependent helicase NAM7

1

0

Small-scale

0.460

High

809068

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.460

High

402002

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

594370

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

707104

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

738843

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

806273

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

Small-scale

0.458

High

809048

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

Small-scale

0.458

High

809060

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

809065

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

804080

GIC1
GTPase-interacting component 1

1

1

High-throughput

0.457

High

809064

GIC2
GTPase-interacting component 2

1

1

High-throughput

0.457

High

392732

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

481624

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

523959

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

670710

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

676002

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

809044

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

809057

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

453603

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

592254

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

653858

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

809041

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

809049

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

809062

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

561310

DPOLA
DNA polymerase alpha catalytic subunit A

2

0

High-throughput

0.324

High

553992

TCPA
T-complex protein 1 subunit alpha

2

0

High-throughput

0.307

High

736553

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High

803350

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.282

High

807802

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.265

Low

453025

CBP8
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.249

Low

613767

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

796207

CDS1
Phosphatidate cytidylyltransferase

1

0

High-throughput

0.249

Low

809050

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low

809067

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

796265

REG2
Protein REG2

1

0

High-throughput

0.238

Low

626738

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025