HitPredict

Interactor 1: UTRN (P46939)
Utrophin (Dystrophin-related protein 1) (DRP-1)
Gene: UTRN

Interactor 2: PK3CG (P48736)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)
Gene: PIK3CG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 3433 Hs			1 1102
+	Hs
		809190 UTRN_HUMAN (1-3433): 0: 1138: 100.00		PI4KB_HUMAN (826-1094): 5.93e-90: 309: 29.52
+	Hs
		164577 SPTN2_HUMAN (778-2566): 3.09e-20: 101: 11.53		PK3CA_HUMAN (23-1093): 0: 1030: 32.92
+	Hs
		787208 SPTB2_HUMAN (1624-2926): 1.69e-18: 96.3: 9.49		PK3CA_HUMAN (23-1093): 0: 1030: 32.92
+	Hs
		787236 PLEC_HUMAN (1861-3399): 1.04e-13: 80.5: 10.71		PK3CA_HUMAN (23-1093): 0: 1030: 32.92
+	Hs
		128775 ACTN4_HUMAN (33-526): 5.25e-49: 193: 31.70		P3C2A_HUMAN (166-1095): 0: 762: 27.12
+	Dm
		1179572 Q7KV70_DROME (664-2807): 2.98e-73: 277: 12.61		Q7K3H0_DROME (300-1095): 0: 669: 28.35
+	Hs
		1038116 PLEC_HUMAN (1861-3399): 1.04e-13: 80.5: 10.71		ATR_HUMAN (698-1083): 1.77e-92: 328: 18.08