HitPredict

Interactor 1: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Interactor 2: LSM6 (Q06406)
U6 snRNA-associated Sm-like protein LSm6
Gene: LSM6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.980

Property	Details
Experiments	10900456, 10428970, 10747033, 11805826, 16554755, 16429126, 14759368, 17513695, 18719247, 19111170, 37968396, 22450758
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Sc			1 86
+	At
		1228011 LSM1B_ARATH (28-162): 5.17e-37: 125: 32.59		LSM6A_ARATH (1-83): 9.34e-34: 112: 41.86
+	Hs
		167681 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Hs
		167678 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Hs
		321388 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Dm
		1376063 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		Q9W2P5_DROME (13-85): 1.72e-31: 106: 42.47
+	Hs
		321386 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Hs
		912220 RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Dm
		1097032 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		RUXF_DROME (12-82): 2.82e-29: 101: 35.21
+	Hs
		538893 RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	At
		1340905 LSM7_ARATH (28-120): 4.87e-25: 94.4: 25.00		LSM6A_ARATH (1-83): 9.34e-34: 112: 41.86
+	Hs
		912021 RUXG_HUMAN (41-117): 5.65e-24: 90.9: 28.57		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Hs
		912256 LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Hs
		911801 RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Hs
		538890 RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Sc
		865982 LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97		LSM6_YEAST (1-86): 9.43e-30: 102: 100.00
+	Hs
		911790 RUXG_HUMAN (41-117): 5.65e-24: 90.9: 28.57		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Hs
		911992 LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Sc
		811668 LSM8_YEAST (43-150): 4.47e-21: 84.7: 18.52		LSM6_YEAST (1-86): 9.43e-30: 102: 100.00
+	Sc
		865976 LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97		RUXF_YEAST (12-83): 5.95e-24: 87.8: 28.77
+	Sc
		811658 LSM8_YEAST (43-150): 4.47e-21: 84.7: 18.52		RUXF_YEAST (12-83): 5.95e-24: 87.8: 28.77