HitPredict

Interactor 1: SMC3 (P47037)
Structural maintenance of chromosomes protein 3 (DA-box protein SMC3)
Gene: SMC3

Interactor 2: NUM1 (Q00402)
Nuclear migration protein NUM1
Gene: NUM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.548

Property	Details
Experiments	11087867, 38781029
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1230 Sc			1 2748
+	Sp
		193869 SMC3_SCHPO (1-1223): 1.52e-78: 284: 33.20		SMC3_SCHPO (60-490): 3.64e-52: 205: 13.96
+	Sp
		193871 SMC1_SCHPO (2-1215): 9.46e-66: 246: 16.94		SMC3_SCHPO (60-490): 3.64e-52: 205: 13.96
+	Sc
		810757 SMC3_YEAST (1-1230): 4.94e-108: 370: 100.00		SMC3_YEAST (8-792): 8.28e-10: 66.8: 14.30
+	Hs
		149432 SMC3_HUMAN (1-1228): 4.16e-91: 322: 30.20		CTRO_HUMAN (749-1403): 1.07e-16: 89.9: 13.13
+	Hs
		1357882 SMC3_HUMAN (1-1228): 4.16e-91: 322: 30.20		SMC3_HUMAN (7-811): 1.07e-14: 83: 12.08
+	Mm
		1321813 SMC1A_MOUSE (2-1222): 6.7e-73: 268: 16.41		SMC3_MOUSE (91-896): 9.91e-29: 129: 14.59
+	Xl
		292736 SMC3_XENLA (1-1228): 4.69e-90: 318: 30.15		SMC3_XENLA (7-811): 1.92e-12: 75.6: 11.85
+	Hs
		728528 SMC3_HUMAN (1-1228): 4.16e-91: 322: 30.20		MYH11_HUMAN (745-1424): 8.09e-10: 67.1: 14.54
+	Hs
		1068704 SMC3_HUMAN (1-1228): 4.16e-91: 322: 30.20		PLEC_HUMAN (171-1310): 3.75e-09: 64.8: 12.51
+	Mm
		1265313 SMC1B_MOUSE (2-1228): 1.11e-67: 252: 17.91		SMC3_MOUSE (91-896): 9.91e-29: 129: 14.59
+	Hs
		311648 SMC2_HUMAN (1-1229): 1.89e-77: 281: 19.00		SMC3_HUMAN (7-811): 1.07e-14: 83: 12.08
+	Hs
		148819 SMC1A_HUMAN (2-1222): 6.7e-73: 268: 16.41		CTRO_HUMAN (749-1403): 1.07e-16: 89.9: 13.13
+	Hs
		149344 SMC4_HUMAN (1-1219): 1.07e-72: 267: 17.04		CTRO_HUMAN (749-1403): 1.07e-16: 89.9: 13.13
+	Bt
		333283 SMC1A_BOVIN (2-1222): 6.7e-73: 268: 16.41		SMC3_BOVIN (7-811): 7.04e-15: 83.7: 12.08
+	Hs
		1057429 SMC1A_HUMAN (2-1222): 6.7e-73: 268: 16.41		SMC3_HUMAN (7-811): 1.07e-14: 83: 12.08
+	Hs
		1242602 SMC1B_HUMAN (2-1228): 1.12e-66: 248: 15.27		SMC3_HUMAN (7-811): 1.07e-14: 83: 12.08
+	Xl
		292725 SMC1A_XENLA (2-1222): 2.68e-67: 250: 16.09		SMC3_XENLA (7-811): 1.92e-12: 75.6: 11.85
+	Xl
		292733 SMC1A_XENLA (2-1222): 2.68e-67: 250: 16.09		Q8AW91_XENLA (7-811): 1.8e-12: 75.6: 11.85
+	Sc
		700779 SMC1_YEAST (2-1215): 4.84e-68: 253: 16.53		SMC3_YEAST (8-792): 8.28e-10: 66.8: 14.30
+	Sc
		810789 SMC4_YEAST (1-1213): 6.29e-65: 244: 15.49		SMC3_YEAST (8-792): 8.28e-10: 66.8: 14.30