HitPredict

Interactor 1: MTR4 (P47047)
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4)
Gene: MTR4

Interactor 2: TRF5 (P48561)
Poly(A) RNA polymerase protein 1 (EC 2.7.7.19) (Topoisomerase 1-related protein TRF5)
Gene: TRF5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 15935758, 16554755, 37968396, 15828860, 16374505, 25589546, 32561742, 23143101
Identification Methods affinity chromatography technology, two hybrid, pull down, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000292 - RNA fragment catabolic process
GO:0003729 - mRNA binding
GO:0005730 - nucleolus
GO:0031499 - TRAMP complex
GO:0034475 - U4 snRNA 3'-end processing
and 4 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1073
Sc

1 642
+ Sc
+ Sp
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024