Interactor 1: MTR4 (P47047)
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4)
Gene: MTR4

Interactor 2: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 25319414, 37968396, 12837249, 28539363, 29176610, 19707589, 14759368, 15828860
Identification Methods pull down, affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~HRDC, HRDC~Helicase_C
Common GO terms GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006401 - RNA catabolic process
GO:0034475 - U4 snRNA 3'-end processing
and 6 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1073
Sc

1 733
+ Hs
+ Hs
+ Sp
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024