Protein: TSC11
Target of rapamycin complex 2 subunit TSC11 (TORC2 subunit TSC11) (Adheres voraciously to TOR2 protein 3) (Temperature-sensitive CSG2 suppressor protein 11)

Gene: TSC11
Organism: Saccharomyces cerevisiae S288C
Interactions: 124
UniProt ID: P40061

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005774 - vacuolar membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743390

TOR2
Serine/threonine-protein kinase TOR2

13

9

Small-scale

0.980

High

817728

LST8
Target of rapamycin complex subunit LST8

4

5

Small-scale

0.694

High

817762

AVO2
Target of rapamycin complex 2 subunit AVO2

4

6

Small-scale

0.683

High

817736

BIT61
Target of rapamycin complex 2 subunit BIT61

4

1

Small-scale

0.677

High

817773

AVO1
Target of rapamycin complex 2 subunit AVO1

4

0

Small-scale

0.653

High

817719

TSC11
Target of rapamycin complex 2 subunit TSC11

1

1

High-throughput

0.618

High

817723

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

3

0

Small-scale

0.613

High

574686

KSS1
Mitogen-activated protein kinase KSS1

2

2

High-throughput

0.574

High

524083

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

526806

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

545036

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.571

High

798529

BIT2
Probable target of rapamycin complex 2 subunit BIT2

1

1

High-throughput

0.541

High

554700

YPK1
Serine/threonine-protein kinase YPK1

1

8

High-throughput

0.536

High

817750

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

Small-scale

0.501

High

548701

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.481

High

737091

CDC11
Cell division control protein 11

1

1

High-throughput

0.481

High

743663

PEP7
Vacuolar segregation protein PEP7

1

1

High-throughput

0.481

High

748221

VAM7
Vacuolar morphogenesis protein 7

1

1

High-throughput

0.481

High

809186

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.481

High

815016

SNF7
Vacuolar-sorting protein SNF7

1

2

High-throughput

0.481

High

817729

BNI1
Protein BNI1

1

2

High-throughput

0.481

High

817737

SNX4
Sorting nexin-4

1

1

High-throughput

0.481

High

817757

SNX41
Sorting nexin-41

1

2

High-throughput

0.481

High

817759

VPS20
Vacuolar protein sorting-associated protein 20

1

2

High-throughput

0.481

High

817771

LUC7
Protein LUC7

1

1

High-throughput

0.481

High

817776

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.481

High

817782

VPS5
Vacuolar protein sorting-associated protein 5

1

1

High-throughput

0.481

High

677754

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.460

High

804895

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.460

High

817722

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.460

High

817725

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.460

High

817730

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

817738

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.460

High

817758

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.460

High

817769

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

817778

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

817756

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

817770

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

392802

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

579473

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.445

High

670764

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

676034

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741666

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

804192

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

817720

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

477566

MYO1
Myosin-1

1

3

High-throughput

0.439

High

548210

BIK1
Nuclear fusion protein BIK1

1

3

High-throughput

0.439

High

643640

SNF2
Transcription regulatory protein SNF2

1

3

High-throughput

0.439

High

646045

KIN3
Serine/threonine-protein kinase KIN3

1

4

High-throughput

0.439

High

750677

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.439

High

753090

NIP80
Protein NIP100

1

5

High-throughput

0.439

High

755243

NUF2
Kinetochore protein NUF2

1

1

High-throughput

0.439

High

758095

CASP
Protein CASP

1

4

High-throughput

0.439

High

779761

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.439

High

817721

TBP6
Probable 26S proteasome subunit YTA6

1

4

High-throughput

0.439

High

817726

MAD1
Spindle assembly checkpoint component MAD1

1

4

High-throughput

0.439

High

817731

GCN20
Protein GCN20

1

3

High-throughput

0.439

High

817745

PRS10
26S proteasome subunit RPT4

1

4

High-throughput

0.439

High

817746

IPI3
Pre-rRNA-processing protein IPI3

1

6

High-throughput

0.439

High

817752

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

High-throughput

0.439

High

817775

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.439

High

817774

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

High-throughput

0.438

High

444529

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

617944

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

7

Small-scale

0.437

High

653864

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

577142

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.407

High

671644

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

752311

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

810815

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.407

High

810951

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.407

High

811095

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.407

High

816225

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.407

High

817734

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

817735

STU2
Protein STU2

1

2

High-throughput

0.407

High

817739

TCPQ
T-complex protein 1 subunit theta

1

4

High-throughput

0.407

High

382124

H4
Histone H4

2

0

High-throughput

0.307

High

817724

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

817742

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.300

High

438304

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.251

Low

639498

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

682880

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.251

Low

700008

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.251

Low

749677

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

776441

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

776755

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

780270

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

782939

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.251

Low

796314

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

796806

EXO84
Exocyst complex component EXO84

1

0

High-throughput

0.251

Low

797179

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

797881

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.251

Low

803294

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

806434

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

813801

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

816988

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

817727

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.251

Low

817732

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

817733

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

817740

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

817741

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.251

Low

817743

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.251

Low

817744

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

817748

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

817749

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

817751

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.251

Low

817753

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.251

Low

817754

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.251

Low

817755

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.251

Low

817761

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

817763

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

817764

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.251

Low

817765

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.251

Low

817766

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit CNL1

1

0

High-throughput

0.251

Low

817767

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

817768

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.251

Low

817772

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

817779

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

817781

TMA17
Translation machinery-associated protein 17

1

0

High-throughput

0.251

Low

817783

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

817780

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.249

Low

817747

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

817760

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

817777

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025