HitPredict

Interactor 1: MPP10 (P47083)
U3 small nucleolar RNA-associated protein MPP10 (U3 snoRNA-associated protein MPP10) (M phase phosphoprotein 10)
Gene: MPP10

Interactor 2: UTP21 (Q06078)
U3 small nucleolar RNA-associated protein 21 (U3 snoRNA-associated protein 21) (U three protein 21)
Gene: UTP21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	15590835, 28600509, 37968396, 20884785
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 593 Sc			1 939
+	Sc
		811579 MPP10_YEAST (1-593): 4.03e-82: 270: 100.00		UTP12_YEAST (11-323): 6.77e-59: 220: 10.06
+	Hs
		1345855 MDN1_HUMAN (1-592): 8.72e-80: 277: 9.95		NLE1_HUMAN (653-785): 5.4e-17: 86.9: 9.70
+	Sc
		635602 MPP10_YEAST (1-593): 4.03e-82: 270: 100.00		PWP2_YEAST (2-230): 8.49e-13: 74.6: 8.86
+	Sc
		630897 MDN1_YEAST (22-429): 1.25e-18: 92.6: 12.03		NLE1_YEAST (498-782): 6.55e-57: 206: 12.69
+	Hs
		133215 MPP10_HUMAN (33-593): 1.24e-56: 204: 23.49		NLE1_HUMAN (653-785): 5.4e-17: 86.9: 9.70
+	Sp
		252177 MDN1_SCHPO (19-342): 4.33e-27: 119: 9.62		NLE1_SCHPO (576-832): 4.18e-37: 148: 15.65