Interactor 1: VPS25 (P47142)
Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25)
Gene: VPS25

Interactor 2: VPS36 (Q06696)
Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36)
Gene: VPS36

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.90 0.908

The method score is based on:

Property Details
Experiments 11283351, 22579254, 15086794, 15469844, 18719252, 37968396, 23063125
Identification Methods two hybrid pooling approach, pull down, two hybrid, x-ray crystallography, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EAP30~ESCRT-II
Common GO terms GO:0000433 - carbon catabolite repression of transcription from RNA polymerase II promoter by glucose
GO:0000814 - ESCRT II complex
GO:0006623 - protein targeting to vacuole
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024