Interactor 1: CENPK (P47167)
Inner kinetochore subunit MCM22 (CENP-K homolog) (Constitutive centromere-associated network protein MCM22) (Minichromosome maintenance protein 22)
Gene: MCM22

Interactor 2: CENPH (Q12262)
Inner kinetochore subunit MCM16 (CENP-H homolog) (Constitutive centromere-associated network protein MCM16) (Minichromosome maintenance protein 16)
Gene: MCM16

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.55 0.727

The method score is based on:

Property Details
Experiments 11283351, 10688190, 11782448, 27524485, 17634282, 37968396, 32997987, 12408861, 16554755, 18719252, 22561346, 16429126
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0034087 - establishment of mitotic sister chromatid cohesion
and 2 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024