Protein: SWI3
SWI/SNF complex subunit SWI3 (Transcription factor TYE2) (Transcription regulatory protein SWI3)

Gene: SWI3
Organism: Saccharomyces cerevisiae S288C
Interactions: 122
UniProt ID: P32591

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

643619

SNF2
Transcription regulatory protein SNF2

19

20

Small-scale

0.986

High

614809

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

8

15

Small-scale

0.974

High

483761

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

6

0

Small-scale

0.900

High

743048

GCN5
Histone acetyltransferase GCN5

2

20

High-throughput

0.776

High

550039

RAP1
DNA-binding protein RAP1

1

1

Small-scale

0.757

High

743036

SWP82
SWI/SNF global transcription activator complex subunit SWP82

7

1

Small-scale

0.745

High

743041

SNF12
Transcription regulatory protein SNF12

7

19

Small-scale

0.745

High

743054

ARP9
Actin-like protein ARP9

7

19

Small-scale

0.745

High

743061

ARP7
Actin-related protein 7

7

17

Small-scale

0.745

High

743011

TAF14
Transcription initiation factor TFIID subunit 14

7

7

Small-scale

0.742

High

617782

SNF6
Transcription regulatory protein SNF6

13

0

Small-scale

0.728

High

743040

RT102
Regulator of Ty1 transposition protein 102

5

1

Small-scale

0.712

High

381967

H4
Histone H4

4

5

Small-scale

0.680

High

743044

H3
Histone H3

3

19

Small-scale

0.651

High

743026

SNF11
Transcription regulatory protein SNF11

3

0

Small-scale

0.643

High

743012

SPT10
Protein SPT10

1

2

High-throughput

0.618

High

737623

HIR1
Protein HIR1

2

15

Small-scale

0.588

High

743030

RIO2
Serine/threonine-protein kinase RIO2

2

3

High-throughput

0.588

High

381024

H2B1
Histone H2B.1

2

20

Small-scale

0.585

High

743028

LAA1
AP-1 accessory protein LAA1

2

1

High-throughput

0.571

High

743060

RIO1
Serine/threonine-protein kinase RIO1

2

3

High-throughput

0.571

High

743009

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

Small-scale

0.559

High

672991

PHO87
Inorganic phosphate transporter PHO87

1

1

High-throughput

0.553

High

743029

PHO90
Low-affinity phosphate transporter PHO90

1

1

High-throughput

0.553

High

626484

AP1
AP-1-like transcription factor YAP1

1

1

High-throughput

0.536

High

721786

XPO1
Exportin-1

1

4

High-throughput

0.536

High

743018

RTG3
Retrograde regulation protein 3

1

1

High-throughput

0.536

High

743047

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.536

High

737662

HIR2
Protein HIR2

1

7

Small-scale

0.515

High

743032

SECU
Securin

1

0

High-throughput

0.513

High

381454

H2B2
Histone H2B.2

1

20

Small-scale

0.501

High

419390

H2A1
Histone H2A.1

1

12

Small-scale

0.501

High

419660

H2A2
Histone H2A.2

1

12

Small-scale

0.501

High

743039

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

High-throughput

0.489

High

408400

GAL4
Regulatory protein GAL4

1

4

Small-scale

0.481

High

547776

NHP6A
Non-histone chromosomal protein 6A

1

20

Small-scale

0.481

High

547860

NHP6B
Non-histone chromosomal protein 6B

1

20

Small-scale

0.481

High

149661

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

383591

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

410012

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

433528

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

434941

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435856

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

441794

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

454948

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

502929

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

504113

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

512333

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

512895

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

514531

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

594265

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

647729

RFA1
Replication factor A protein 1

1

4

Small-scale

0.479

High

674498

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

689344

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

706550

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

734895

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

740388

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

Small-scale

0.479

High

743001

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

5

High-throughput

0.479

High

743002

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

743003

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

743005

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

743013

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

743014

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

743015

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

743021

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.479

High

743022

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

743023

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

7

High-throughput

0.479

High

743031

RT106
Histone chaperone RTT106

1

1

High-throughput

0.479

High

743033

MPH1
ATP-dependent DNA helicase MPH1

1

6

High-throughput

0.479

High

743034

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

743037

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

743042

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

743045

NAM8
Protein NAM8

1

1

High-throughput

0.479

High

743046

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

743049

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

6

High-throughput

0.479

High

743052

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

743053

SIZ1
E3 SUMO-protein ligase SIZ1

1

5

High-throughput

0.479

High

743056

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

Small-scale

0.479

High

743057

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.479

High

743058

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

743059

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

743063

CMR1
DNA damage-binding protein CMR1

1

12

High-throughput

0.479

High

743064

SMC6
Structural maintenance of chromosomes protein 6

1

6

High-throughput

0.479

High

743004

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

743008

NUF2
Kinetochore protein NUF2

1

0

High-throughput

0.460

High

553523

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

742999

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

743000

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

743051

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

743055

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

392439

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

394374

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

448154

HAP2
Transcriptional activator HAP2

1

4

High-throughput

0.445

High

481546

HSP73
Heat shock protein SSA3

1

6

High-throughput

0.445

High

523400

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

526215

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

544217

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

645600

AFT1
Iron-regulated transcriptional activator AFT1

1

2

High-throughput

0.445

High

671509

SWI4
Regulatory protein SWI4

1

11

High-throughput

0.445

High

736618

ASF1
Histone chaperone ASF1

1

3

High-throughput

0.445

High

738730

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.445

High

739323

ZUO1
Zuotin

1

2

High-throughput

0.445

High

743006

MSN2
Zinc finger protein MSN2

1

13

High-throughput

0.445

High

743007

MSN4
Zinc finger protein MSN4

1

13

High-throughput

0.445

High

743010

SPT7
SAGA complex subunit SPT7

1

20

High-throughput

0.445

High

743025

SPT8
SAGA complex subunit SPT8

1

1

High-throughput

0.445

High

743043

CRZ1
Transcriptional regulator CRZ1

1

6

High-throughput

0.445

High

743050

GIS1
Transcriptional activator/repressor GIS1

1

10

High-throughput

0.445

High

743062

CAF1A
Chromatin assembly factor 1 subunit A

1

5

High-throughput

0.445

High

511760

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.426

High

743024

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

743035

SYS1
Protein SYS1

1

0

High-throughput

0.426

High

592116

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.407

High

743016

CDC27
Anaphase-promoting complex subunit CDC27

1

6

High-throughput

0.407

High

743038

CWC23
Pre-mRNA-splicing factor CWC23

1

2

High-throughput

0.407

High

613798

SPO7
Sporulation-specific protein SPO7

2

0

High-throughput

0.307

High

743017

RM16
Large ribosomal subunit protein uL16m

2

0

High-throughput

0.307

High

365908

PPA5
Repressible acid phosphatase

1

0

High-throughput

0.279

Low

743020

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

743027

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.249

Low

364990

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

743019

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025