HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~F-actin_cap_A
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 375
+	Hs
		812976 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		857090 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		857100 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		812987 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		812988 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Hs
		857101 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Dm
		862585 CAPZA_DROME (5-284): 3.22e-140: 397: 60.99		ACT3_DROME (2-375): 0: 596: 94.92