HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~F_actin_cap_B
Common GO terms	GO:0005829 - cytosol GO:0008290 - F-actin capping protein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 118
+	Bt
		945192 CAPZB_BOVIN (2-272): 2.07e-177: 492: 100.00		MTPN_BOVIN (1-118): 5.13e-42: 135: 100.00
+	Rn
		917048 CAPZB_RAT (1-272): 4.35e-177: 490: 100.00		MTPN_RAT (1-118): 5.02e-42: 135: 99.15
+	Hs
		813799 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		RAI14_HUMAN (2-99): 2.66e-26: 103: 27.72
+	Hs
		813264 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		DAPK1_HUMAN (2-87): 6.05e-24: 96.8: 27.91
+	Hs
		161331 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		MYPT1_HUMAN (4-87): 2.11e-16: 75.5: 25.00
+	Hs
		257581 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ANR17_HUMAN (2-93): 3.25e-11: 60.8: 36.96