HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~F_actin_cap_B
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 376
+	Hs
		785520 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTY_HUMAN (1-376): 0: 728: 90.43
+	Hs
		813287 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTB_HUMAN (7-376): 0: 580: 52.41
+	Hs
		813366 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTG_HUMAN (7-376): 0: 580: 52.67
+	Hs
		813370 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTC_HUMAN (5-376): 0: 576: 52.93
+	Dm
		820547 CAPZB_DROME (1-269): 1.72e-166: 463: 81.78		ACT3_DROME (7-376): 0: 574: 52.14