HitPredict

Interactor 1: ID4 (P47928)
DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)
Gene: ID4

Interactor 2: OLIG1 (Q8TAK6)
Oligodendrocyte transcription factor 1 (Oligo1) (Class B basic helix-loop-helix protein 6) (bHLHb6) (Class E basic helix-loop-helix protein 21) (bHLHe21)
Gene: OLIG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15280210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046983 - protein dimerization activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 161 Hs			1 271
+	Mm
		781014 ID4_MOUSE (1-161): 3.39e-62: 190: 98.14		OLIG1_MOUSE (1-271): 1.53e-54: 178: 82.29
+	Hs
		970588 ID2_HUMAN (1-148): 2.51e-41: 136: 43.24		OLIG1_HUMAN (1-271): 2.16e-58: 189: 100.00
+	Hs
		814906 ID4_HUMAN (1-161): 1.67e-63: 194: 100.00		OLIG2_HUMAN (41-254): 4.45e-32: 122: 32.39
+	Mm
		781011 ID2_MOUSE (1-148): 1.17e-41: 137: 42.57		OLIG1_MOUSE (1-271): 1.53e-54: 178: 82.29
+	Hs
		546072 ID4_HUMAN (1-161): 1.67e-63: 194: 100.00		MYOG_HUMAN (32-236): 3.01e-30: 114: 16.67
+	Mm
		781013 ID4_MOUSE (1-161): 3.39e-62: 190: 98.14		OLIG2_MOUSE (41-254): 2.08e-30: 117: 31.98
+	Hs
		814916 ID4_HUMAN (1-161): 1.67e-63: 194: 100.00		NGN3_HUMAN (40-228): 1.5e-27: 107: 22.55
+	Hs
		568188 ID4_HUMAN (1-161): 1.67e-63: 194: 100.00		TAL1_HUMAN (17-254): 3.52e-26: 106: 18.33
+	Hs
		616610 ID4_HUMAN (1-161): 1.67e-63: 194: 100.00		MYF6_HUMAN (22-206): 9.62e-26: 103: 18.62
+	Hs
		526742 ID1_HUMAN (12-161): 1.12e-51: 163: 37.42		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83
+	Hs
		546071 ID1_HUMAN (12-161): 1.12e-51: 163: 37.42		MYOG_HUMAN (32-236): 3.01e-30: 114: 16.67
+	Hs
		526743 ID2_HUMAN (1-148): 2.51e-41: 136: 43.24		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83
+	Mm
		589139 ID1_MOUSE (35-149): 7.26e-47: 152: 40.00		TAL1_MOUSE (21-254): 2.09e-26: 107: 20.09
+	Hs
		970566 ID2_HUMAN (1-148): 2.51e-41: 136: 43.24		OLIG2_HUMAN (41-254): 4.45e-32: 122: 32.39
+	Mm
		781010 ID2_MOUSE (1-148): 1.17e-41: 137: 42.57		OLIG2_MOUSE (41-254): 2.08e-30: 117: 31.98
+	Hs
		526744 ID3_HUMAN (1-135): 2.13e-33: 116: 44.44		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83