HitPredict

Interactor 1: CRKL (P47941)
Crk-like protein
Gene: CRKL

Interactor 2: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	15110774, 15316068, 15062102
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0016358 - dendrite development GO:0021766 - hippocampus development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 303 Mm			1 588
+	Hs
		269125 CRKL_HUMAN (1-303): 3.37e-76: 236: 96.70		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Mm
		956229 CRK_MOUSE (3-302): 1.23e-60: 196: 54.57		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		269124 CRK_HUMAN (3-302): 1.68e-60: 196: 54.57		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Mm
		956228 PLCG1_MOUSE (3-202): 3.95e-30: 122: 18.52		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		208964 NCK2_HUMAN (13-98): 1.08e-18: 87.4: 31.03		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		269176 SH3K1_HUMAN (198-297): 3.86e-16: 80.5: 23.53		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Mm
		292683 GRAP2_MOUSE (2-294): 3.05e-44: 155: 14.53		SHC1_MOUSE (23-354): 1.58e-37: 148: 12.24
+	Dm
		957161 GRAP_DROME (126-293): 2.39e-27: 107: 15.87		DAB_DROME (2-583): 9.69e-46: 176: 17.93
+	Rn
		924995 GRB2_RAT (126-297): 7.67e-29: 111: 15.28		SHC1_RAT (8-354): 9.65e-46: 169: 12.53
+	Ce
		283752 VAV_CAEEL (14-185): 1.38e-26: 111: 21.35		CED6_CAEEL (5-482): 3.11e-42: 160: 14.58
+	Mm
		957139 GRB2_MOUSE (126-297): 5.09e-29: 112: 15.28		DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71
+	Hs
		924477 GRB2_HUMAN (126-297): 7.67e-29: 111: 15.28		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		203218 GRB2_HUMAN (126-297): 7.67e-29: 111: 15.28		SYNJ1_HUMAN (96-584): 6.97e-37: 149: 12.08
+	Mm
		957235 GRB2_MOUSE (126-297): 5.09e-29: 112: 15.28		SHC1_MOUSE (23-354): 1.58e-37: 148: 12.24
+	Hs
		209098 NCK2_HUMAN (13-98): 1.08e-18: 87.4: 31.03		ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81
+	Dm
		993194 GRAP_DROME (126-293): 2.39e-27: 107: 15.87		Q9V3C8_DROME (15-288): 7.82e-39: 149: 13.16
+	Hs
		1115812 SH3K1_HUMAN (198-297): 3.86e-16: 80.5: 23.53		Q49AR9_HUMAN (11-321): 2.68e-43: 164: 15.87
+	Hs
		1268487 SH3K1_HUMAN (198-297): 3.86e-16: 80.5: 23.53		ANS1A_HUMAN (11-241): 5.57e-39: 155: 17.02
+	Hs
		957207 SH3K1_HUMAN (198-297): 3.86e-16: 80.5: 23.53		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		203241 SH3K1_HUMAN (198-297): 3.86e-16: 80.5: 23.53		SYNJ1_HUMAN (96-584): 6.97e-37: 149: 12.08