HitPredict

Interactor 1: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Interactor 2: SNX33 (Q8WV41)
Sorting nexin-33 (SH3 and PX domain-containing protein 3)
Gene: SNX33

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	26186194, 28514442, 33961781, 19807924, 24291222
Identification Methods	affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, phage display
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 574
+	Hs
		815720 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		SNX9_HUMAN (1-571): 1.57e-139: 419: 34.18
+	Hs
		815707 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		SNX18_HUMAN (1-491): 9.22e-118: 363: 45.84