Interactor 1: SDF1 (P48061)
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
Gene: CXCL12
Interactor 2: CXCL6 (P80162)
C-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3]
Gene: CXCL6
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28381538 |
| Identification Methods | pull down, surface plasmon resonance, filter binding |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL8~IL8 |
| Common GO terms | GO:0005576 - extracellular region GO:0006935 - chemotaxis GO:0007165 - signal transduction GO:0008009 - chemokine activity GO:0045236 - CXCR chemokine receptor binding and 1 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
