Protein: DXO
Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-)

Gene: DXO
Organism: Homo sapiens
Interactions: 40
UniProt ID: O77932

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000287 - magnesium ion binding
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

305821

RECQ5
ATP-dependent DNA helicase Q5

3

1

High-throughput

0.667

High

305849

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.656

High

305842

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

3

0

High-throughput

0.638

High

305846

ARMC5
Armadillo repeat-containing protein 5

3

0

High-throughput

0.638

High

305820

DXO
Decapping and exoribonuclease protein

1

0

High-throughput

0.622

High

305843

XRN1
5'-3' exoribonuclease 1

1

4

High-throughput

0.621

High

305827

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.515

High

305831

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.515

High

305840

EXOS7
Exosome complex component RRP42

1

1

High-throughput

0.508

High

305850

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.508

High

305833

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.494

High

305829

COF1
Cofilin-1

1

0

High-throughput

0.493

High

305838

SBP1
Methanethiol oxidase

1

0

High-throughput

0.493

High

159944

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

167207

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

240330

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.493

High

274413

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

282549

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.493

High

305823

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

305824

VIME
Vimentin

1

0

High-throughput

0.493

High

305828

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.493

High

305830

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.493

High

305832

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

305834

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

305835

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

0

High-throughput

0.493

High

305848

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.493

High

305851

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

305836

EXOSX
Exosome complex component 10

1

0

High-throughput

0.486

High

305845

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.486

High

305847

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.486

High

305844

NPL4
Nuclear protein localization protein 4 homolog

1

0

Small-scale

0.458

High

305839

FLOT2
Flotillin-2

1

0

Small-scale

0.438

High

305822

IGHA2
Immunoglobulin heavy constant alpha 2

1

0

High-throughput

0.426

High

305841

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

2

0

High-throughput

0.305

High

245837

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301277

WFS1
Wolframin

1

0

High-throughput

0.268

Low

305837

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

305825

MYZAP
Myocardial zonula adherens protein

1

0

High-throughput

0.232

Low

305826

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025