HitPredict

Interactor 1: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Interactor 2: Q9VW59 (Q9VW59)
LD16419p (RhoGDI, isoform A) (RhoGDI, isoform B)
Gene: RhoGDI

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Rho_GDI
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 201
+	Hs
		854769 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	Mm
		925816 RAC1_MOUSE (1-192): 1.19e-80: 239: 57.73		GDIR1_MOUSE (2-200): 5.39e-99: 287: 46.73
+	Rn
		901290 RHOA_RAT (1-192): 6.41e-79: 235: 86.53		GDIR1_RAT (2-200): 5.39e-99: 287: 46.73
+	Hs
		854763 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	Hs
		854771 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	Hs
		545278 RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	Hs
		436218 RHOC_HUMAN (1-192): 5.91e-76: 227: 85.49		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	Hs
		854760 CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89		GDIR1_HUMAN (2-200): 1.73e-99: 288: 48.24
+	At
		1105129 RAC3_ARATH (1-182): 1.32e-84: 249: 49.73		GDIR_ARATH (1-200): 8.95e-86: 254: 38.00
+	Hs
		854851 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		GDIR2_HUMAN (1-200): 5.46e-90: 263: 45.05
+	Hs
		925561 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		GDIR3_HUMAN (1-200): 1.03e-88: 261: 42.50
+	Hs
		854852 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		GDIR2_HUMAN (1-200): 5.46e-90: 263: 45.05
+	Hs
		900840 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		GDIR3_HUMAN (1-200): 1.03e-88: 261: 42.50
+	Hs
		545279 RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16		GDIR2_HUMAN (1-200): 5.46e-90: 263: 45.05
+	Hs
		951270 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		GDIR3_HUMAN (1-200): 1.03e-88: 261: 42.50
+	Hs
		894357 CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89		GDIR3_HUMAN (1-200): 1.03e-88: 261: 42.50
+	Sc
		419734 RHO1_YEAST (3-184): 1.73e-90: 264: 72.53		GDIR_YEAST (1-198): 8.6e-71: 215: 37.75
+	Ce
		975573 RAC1_CAEEL (1-192): 8.01e-80: 237: 54.40		GDIR_CAEEL (11-199): 2.8e-74: 223: 43.16
+	Ce
		1093791 RHO1_CAEEL (1-192): 9.83e-77: 229: 85.94		GDIR_CAEEL (11-199): 2.8e-74: 223: 43.16
+	Cl
		47354 RAC1_CANLF (1-192): 1.19e-80: 239: 57.73		A0A8I3N6C6_CANLF (2-200): 6.9e-64: 196: 35.18