HitPredict

Interactor 1: LEPR (P48357)
Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295)
Gene: LEPR

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 11342028, 9600917
Identification Methods affinity chromatography technology, pull down, surface plasmon resonance, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0019221 - cytokine-mediated signaling pathway
GO:0042593 - glucose homeostasis
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1165
Hs

1 593
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024