HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: SOX21 (Q9Y651)
Transcription factor SOX-21 (SOX-A)
Gene: SOX21

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 26186194, 28514442, 30442713, 33961781, 34732716
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 7 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 317
Hs

1 276
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Last updated: 15 Jul 2024