HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: TYY1 (Q00899)
Transcriptional repressor protein YY1 (Delta transcription factor) (NF-E1) (UCR-motif DNA-binding protein) (Yin and yang 1) (YY-1)
Gene: Yy1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 31077711, 19536159
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 14 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 319
Mm

1 414
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024