HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: DDX17 (Q501J6)
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17)
Gene: DDX17

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0010467 - gene expression GO:0031490 - chromatin DNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 650
+	Hs
		818320 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX17_HUMAN (26-650): 0: 602: 98.88
+	Hs
		1271630 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX17_HUMAN (26-650): 0: 602: 98.88
+	Hs
		571352 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX5_HUMAN (3-637): 0: 532: 65.37
+	Mm
		818738 SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00		Q8BTS0_MOUSE (3-637): 0: 530: 65.27
+	Hs
		996809 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX17_HUMAN (26-650): 0: 602: 98.88
+	Hs
		571557 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX5_HUMAN (3-637): 0: 532: 65.37
+	Hs
		571415 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX5_HUMAN (3-637): 0: 532: 65.37
+	Hs
		133924 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX3X_HUMAN (2-502): 1.65e-147: 444: 39.62
+	Hs
		134175 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX3X_HUMAN (2-502): 1.65e-147: 444: 39.62
+	Hs
		996752 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX42_HUMAN (9-616): 2.38e-150: 460: 34.74
+	Dm
		580724 HMG2_DROME (29-138): 5.13e-13: 70.9: 15.18		DDX17_DROME (36-474): 4.69e-149: 450: 64.40
+	Hs
		331834 NSD2_HUMAN (1-288): 5.77e-29: 119: 11.04		DDX46_HUMAN (47-472): 2.18e-107: 350: 43.38