HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: DCAF5 (Q80T85)
DDB1- and CUL4-associated factor 5 (WD repeat-containing protein 22)
Gene: DCAF5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30442713
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 946
+	Hs
		818355 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DCAF5_HUMAN (1-946): 0: 723: 89.99
+	Hs
		818834 SOX9_HUMAN (27-262): 1.46e-38: 144: 27.24		FBXW7_HUMAN (95-408): 1.24e-65: 236: 16.46
+	Hs
		1281409 TF7L2_HUMAN (46-269): 1.49e-35: 137: 17.78		FBXW7_HUMAN (95-408): 1.24e-65: 236: 16.46
+	Hs
		881823 SOX10_HUMAN (27-221): 3.97e-35: 134: 34.36		FBXW7_HUMAN (95-408): 1.24e-65: 236: 16.46
+	Hs
		996813 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		FBXW7_HUMAN (95-408): 1.24e-65: 236: 16.46
+	Mm
		1142008 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		TBL1R_MOUSE (228-549): 9.52e-36: 144: 9.77
+	Hs
		245575 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		TBL1X_HUMAN (222-553): 3.65e-36: 147: 10.34
+	Hs
		817901 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		RACK1_HUMAN (221-550): 1.9e-37: 144: 12.54
+	Hs
		818441 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		TBL1R_HUMAN (228-549): 1.06e-35: 144: 9.77
+	Hs
		209427 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		PLRG1_HUMAN (49-386): 3.26e-61: 218: 20.52
+	Mm
		818717 SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00		HIRA_MOUSE (2-267): 5.18e-28: 124: 13.87
+	Hs
		929620 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		RACK1_HUMAN (221-550): 1.9e-37: 144: 12.54
+	Hs
		245569 SOX5_HUMAN (17-129): 1.56e-39: 149: 40.71		TBL1X_HUMAN (222-553): 3.65e-36: 147: 10.34
+	Hs
		245585 SOX10_HUMAN (27-221): 3.97e-35: 134: 34.36		TBL1X_HUMAN (222-553): 3.65e-36: 147: 10.34
+	Hs
		245594 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		TBL1X_HUMAN (222-553): 3.65e-36: 147: 10.34
+	Hs
		817868 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		WDR5_HUMAN (1-84): 3.35e-10: 64.5: 15.12
+	Hs
		867896 TF7L2_HUMAN (46-269): 1.49e-35: 137: 17.78		HIRA_HUMAN (2-267): 1.6e-28: 125: 13.87
+	Hs
		903450 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		WDR5_HUMAN (1-84): 3.35e-10: 64.5: 15.12
+	Hs
		996824 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		SNR40_HUMAN (320-538): 1.49e-12: 72.1: 14.16
+	Hs
		903169 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		WDR5_HUMAN (1-84): 3.35e-10: 64.5: 15.12