Interactor 1: SOX9 (P48436)
Transcription factor SOX-9
Gene: SOX9

Interactor 2: RUNX2 (Q13950)
Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)
Gene: RUNX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 20593410, 17142326
Identification Methods fluorescent resonance energy transfer, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002062 - chondrocyte differentiation
and 15 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 509
Hs

1 521
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024