Protein: CAP1
Adenylyl cyclase-associated protein 1 (CAP 1)

Gene: CAP1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q01518

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0001667 - ameboidal-type cell migration
GO:0003779 - actin binding
GO:0005576 - extracellular region
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

952753

ACTB
Actin, cytoplasmic 1

7

20

High-throughput

0.963

High

993137

ACTG
Actin, cytoplasmic 2

4

20

Small-scale

0.900

High

818791

CAP2
Adenylyl cyclase-associated protein 2

3

4

Small-scale

0.877

High

977676

ACTA
Actin, aortic smooth muscle

3

20

High-throughput

0.861

High

996429

ACTS
Actin, alpha skeletal muscle

3

20

High-throughput

0.861

High

506942

POTEI
POTE ankyrin domain family member I

2

20

High-throughput

0.811

High

1030734

ACTBL
Beta-actin-like protein 2

2

20

High-throughput

0.811

High

995545

ACTC
Actin, alpha cardiac muscle 1

2

20

High-throughput

0.776

High

1030720

CAP1
Adenylyl cyclase-associated protein 1

1

4

Small-scale

0.713

High

660036

COF1
Cofilin-1

4

9

Small-scale

0.694

High

1030738

TWF2
Twinfilin-2

3

10

High-throughput

0.662

High

563635

CFTR
Cystic fibrosis transmembrane conductance regulator

3

0

High-throughput

0.638

High

993417

ACTH
Actin, gamma-enteric smooth muscle

1

20

High-throughput

0.618

High

1030748

STYX
Serine/threonine/tyrosine-interacting protein

2

1

Small-scale

0.611

High

1030733

BCL7A
B-cell CLL/lymphoma 7 protein family member A

3

3

High-throughput

0.604

High

1030749

BCL7C
B-cell CLL/lymphoma 7 protein family member C

2

3

High-throughput

0.574

High

934479

TERA
Transitional endoplasmic reticulum ATPase

2

2

High-throughput

0.571

High

791303

SYUA
Alpha-synuclein

2

0

High-throughput

0.561

High

241426

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

389303

FINC
Fibronectin

1

1

High-throughput

0.536

High

529651

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

583536

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

908959

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

1030722

TWF1
Twinfilin-1

1

10

High-throughput

0.536

High

1030746

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

1030756

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.529

High

354852

DNAL4
Dynein axonemal light chain 4

1

0

High-throughput

0.513

High

608251

EGLN
Endoglin

1

0

High-throughput

0.513

High

783559

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

1030721

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

1030741

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.513

High

1030770

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

353256

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.493

High

484500

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

866462

PA24A
Cytosolic phospholipase A2

1

0

Small-scale

0.486

High

1030758

MYOC
Myocilin

1

0

Small-scale

0.480

High

226753

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

2

High-throughput

0.479

High

375419

RASK
GTPase KRas

1

1

High-throughput

0.479

High

408816

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

581516

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.479

High

606645

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

799001

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

867052

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

910294

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

1

High-throughput

0.479

High

1030724

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

1030735

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.479

High

1030739

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1030751

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1030754

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1030763

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1030766

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

337581

FMNL1
Formin-like protein 1

1

0

Small-scale

0.458

High

384136

CO1A1
Collagen alpha-1(I) chain

1

0

High-throughput

0.458

High

400672

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

411757

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

459550

PROF1
Profilin-1

1

0

High-throughput

0.458

High

553171

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

590879

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

642807

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

762302

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

830584

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

872211

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

887983

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

891463

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

957329

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

1030723

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.458

High

1030726

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1030727

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1030729

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1030730

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1030742

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.458

High

1030743

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

1030744

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1030752

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1030755

OXLA
L-amino-acid oxidase

1

0

Small-scale

0.458

High

1030757

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

1030759

PELO
Protein pelota homolog

1

0

High-throughput

0.458

High

1030761

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1030762

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1030764

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1030767

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1030765

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

947340

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

1030736

WLS
Protein wntless homolog

1

0

Small-scale

0.438

High

105773

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

731209

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.437

High

970354

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1030731

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

1030737

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1030753

JARD2
Protein Jumonji

1

1

High-throughput

0.437

High

133487

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.426

High

1030728

S29A2
Equilibrative nucleoside transporter 2

1

0

High-throughput

0.426

High

1030760

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

429746

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

886765

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.373

High

892669

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low

276111

NIPS2
Protein NipSnap homolog 2

1

0

Small-scale

0.249

Low

371793

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

588488

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

685514

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.249

Low

695237

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

767979

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1030725

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.249

Low

1030732

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1030740

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

1030745

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.249

Low

1030747

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.249

Low

1030750

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.249

Low

1030768

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

1030769

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

62489

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025