HitPredict

Interactor 1: RXRG (P48443)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	16169070
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 723
+	Hs
		370206 ESR1_HUMAN (1-458): 9.47e-116: 353: 23.81		LRCH3_HUMAN (11-433): 1.03e-53: 199: 19.38
+	Hs
		264496 ESR1_HUMAN (1-458): 9.47e-116: 353: 23.81		LRCH4_HUMAN (33-390): 5.1e-46: 176: 21.79
+	Hs
		1269361 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		LRCH3_HUMAN (11-433): 1.03e-53: 199: 19.38
+	Hs
		1050096 NR2E1_HUMAN (124-458): 6.16e-113: 339: 31.15		SCRIB_HUMAN (31-234): 3.51e-37: 152: 24.51
+	Hs
		264513 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		LRCH4_HUMAN (33-390): 5.1e-46: 176: 21.79
+	Hs
		914680 ERR3_HUMAN (25-459): 2.4e-113: 343: 29.44		MFHA1_HUMAN (8-200): 2.08e-34: 143: 28.50
+	Hs
		370727 ESR1_HUMAN (1-458): 9.47e-116: 353: 23.81		SHOC2_HUMAN (32-214): 1.09e-31: 132: 28.42
+	Hs
		1050020 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		SCRIB_HUMAN (31-234): 3.51e-37: 152: 24.51
+	Hs
		1269946 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		SHOC2_HUMAN (32-214): 1.09e-31: 132: 28.42
+	Hs
		1269975 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		LRCH1_HUMAN (86-231): 4.12e-26: 116: 19.46
+	Hs
		1269493 ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82		LRRC1_HUMAN (17-165): 2.67e-12: 71.6: 23.49