Protein: ADCY9
Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9)

Gene: ADCY9
Organism: Homo sapiens
Interactions: 166
UniProt ID: O60503

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0004016 - adenylate cyclase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250111

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

2

5

High-throughput

0.776

High

189334

STX7
Syntaxin-7

4

2

High-throughput

0.694

High

127227

LEG8
Galectin-8

3

9

High-throughput

0.667

High

250049

LEG3
Galectin-3

3

9

High-throughput

0.667

High

250054

CD27
CD27 antigen

3

1

High-throughput

0.667

High

250160

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.638

High

250141

GPR21
Probable G-protein coupled receptor 21

2

1

High-throughput

0.628

High

250059

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

250046

AREG
Amphiregulin

3

1

High-throughput

0.609

High

250112

PIANP
PILR alpha-associated neural protein

2

0

High-throughput

0.602

High

250125

S20A1
Sodium-dependent phosphate transporter 1

2

0

High-throughput

0.602

High

230725

EXTL3
Exostosin-like 3

2

1

High-throughput

0.601

High

250122

NLGN2
Neuroligin-2

2

1

High-throughput

0.601

High

250174

MAN1
Inner nuclear membrane protein Man1

2

1

High-throughput

0.601

High

250082

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.586

High

250031

RASK
GTPase KRas

2

8

High-throughput

0.584

High

250080

RHOB
Rho-related GTP-binding protein RhoB

2

12

High-throughput

0.584

High

250146

FUT8
Alpha-(1,6)-fucosyltransferase

2

0

High-throughput

0.576

High

250172

FND3A
Fibronectin type-III domain-containing protein 3A

2

0

High-throughput

0.576

High

250179

ALG5
Dolichyl-phosphate beta-glucosyltransferase

2

0

High-throughput

0.576

High

250071

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

250035

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

250032

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

250057

NOS1
Nitric oxide synthase 1

1

1

High-throughput

0.536

High

250061

V1BR
Vasopressin V1b receptor

1

1

High-throughput

0.536

High

250094

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.536

High

250097

LEG9B
Galectin-9B

1

9

High-throughput

0.536

High

250098

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.536

High

250114

NLGN1
Neuroligin-1

1

1

High-throughput

0.536

High

250118

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

1

High-throughput

0.536

High

250121

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.536

High

250132

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.536

High

250145

CA043
Protein C1orf43

1

2

High-throughput

0.536

High

250149

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

250072

CTXN1
Cortexin-1

1

0

High-throughput

0.513

High

250099

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.513

High

250100

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

0

High-throughput

0.513

High

250102

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

250117

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.513

High

250119

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

250131

TM143
Transmembrane protein 143

1

0

High-throughput

0.513

High

250137

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

0

High-throughput

0.513

High

250159

RPRM
Protein reprimo

1

0

High-throughput

0.513

High

250177

IR3IP
Immediate early response 3-interacting protein 1

1

0

High-throughput

0.513

High

170573

CLGN
Calmegin

1

3

High-throughput

0.489

High

250034

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

1

High-throughput

0.489

High

250108

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

1

High-throughput

0.489

High

250133

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.489

High

250152

DJC18
DnaJ homolog subfamily C member 18

1

2

High-throughput

0.489

High

48453

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

126389

RHOD
Rho-related GTP-binding protein RhoD

1

14

High-throughput

0.479

High

250030

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

250038

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

250039

RHOC
Rho-related GTP-binding protein RhoC

1

10

High-throughput

0.479

High

250041

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.479

High

250043

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

250044

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.479

High

250045

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.479

High

250047

RHOQ
Rho-related GTP-binding protein RhoQ

1

12

High-throughput

0.479

High

250048

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

250052

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

250053

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

250055

CALX
Calnexin

1

3

High-throughput

0.479

High

250056

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.479

High

250064

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

250065

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

250067

RND2
Rho-related GTP-binding protein RhoN

1

15

High-throughput

0.479

High

250068

AFAD
Afadin

1

4

High-throughput

0.479

High

250073

RAC3
Ras-related C3 botulinum toxin substrate 3

1

9

High-throughput

0.479

High

250074

CDC42
Cell division control protein 42 homolog

1

10

High-throughput

0.479

High

250075

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

250076

RHOA
Transforming protein RhoA

1

11

High-throughput

0.479

High

250077

RND3
Rho-related GTP-binding protein RhoE

1

15

High-throughput

0.479

High

250081

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.479

High

250083

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.479

High

250086

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

250088

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

250091

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

250092

RHOH
Rho-related GTP-binding protein RhoH

1

12

High-throughput

0.479

High

250107

RHOU
Rho-related GTP-binding protein RhoU

1

12

High-throughput

0.479

High

250113

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

250115

DJC22
DnaJ homolog subfamily C member 22

1

1

High-throughput

0.479

High

250127

RND1
Rho-related GTP-binding protein Rho6

1

15

High-throughput

0.479

High

250135

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

250136

RHOV
Rho-related GTP-binding protein RhoV

1

9

High-throughput

0.479

High

250140

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.479

High

250142

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

250150

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

250151

RHOJ
Rho-related GTP-binding protein RhoJ

1

12

High-throughput

0.479

High

250154

RHOF
Rho-related GTP-binding protein RhoF

1

13

High-throughput

0.479

High

250155

POPD2
Popeye domain-containing protein 2

1

1

High-throughput

0.479

High

250165

DNJ5B
DnaJ homolog subfamily C member 5B

1

2

High-throughput

0.479

High

250166

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.479

High

250170

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

250180

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.479

High

173785

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

225875

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

250029

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

250036

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

250037

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

250042

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

250050

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

250058

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

250060

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

250062

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

250063

EMD
Emerin

1

0

High-throughput

0.458

High

250066

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

250069

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.458

High

250078

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

250079

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

250087

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

250089

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

250090

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

250093

OCLN
Occludin

1

0

High-throughput

0.458

High

250101

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

250105

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

250110

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

250120

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

250128

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

250130

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

250138

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

250139

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

250144

DERL1
Derlin-1

1

0

High-throughput

0.458

High

250153

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

250157

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

250158

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

250163

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

250164

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

250167

ANC2
Anaphase-promoting complex subunit 2

1

0

High-throughput

0.458

High

250175

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

190288

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.445

High

250033

B3AT
Band 3 anion transport protein

1

3

High-throughput

0.445

High

250070

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

3

High-throughput

0.445

High

250085

LAT1
Large neutral amino acids transporter small subunit 1

1

3

High-throughput

0.445

High

250103

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

250104

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.445

High

250106

NFXL1
NF-X1-type zinc finger protein NFXL1

1

7

High-throughput

0.445

High

250126

YLAT2
Y+L amino acid transporter 2

1

3

High-throughput

0.445

High

250156

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

250169

YLAT1
Y+L amino acid transporter 1

1

3

High-throughput

0.445

High

250173

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.445

High

250176

PLXD1
Plexin-D1

1

5

High-throughput

0.445

High

250051

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.437

High

250147

DJC25
DnaJ homolog subfamily C member 25

1

3

High-throughput

0.437

High

250162

ARL15
ADP-ribosylation factor-like protein 15

1

2

High-throughput

0.437

High

250168

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

1

High-throughput

0.437

High

250171

DJC16
DnaJ homolog subfamily C member 16

1

1

High-throughput

0.437

High

208147

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.426

High

250040

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.426

High

250095

S35G1
Solute carrier family 35 member G1

1

0

High-throughput

0.426

High

250143

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.426

High

250178

FLVC1
Choline/ethanolamine transporter FLVCR1

1

0

High-throughput

0.426

High

250096

SMTL2
Smoothelin-like protein 2

1

1

High-throughput

0.407

High

250124

NET5
Netrin-5

1

6

High-throughput

0.407

High

155535

NEMP1
Nuclear envelope integral membrane protein 1

3

0

High-throughput

0.345

High

250123

PXYP1
2-phosphoxylose phosphatase 1

2

0

High-throughput

0.328

High

156180

CO72L
Cytochrome c oxidase subunit 7A2-like, mitochondrial

1

0

High-throughput

0.279

Low

250134

CLMN
Calmin

1

0

High-throughput

0.279

Low

124163

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

250084

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

250109

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

250129

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

250148

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

250161

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

193657

TPSN
Tapasin

1

0

High-throughput

0.232

Low

250116

SIM20
Small integral membrane protein 20

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025