HitPredict

Interactor 1: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Interactor 2: Q8SY34 (Q8SY34)
LD46604p (Myosin phosphatase targeting subunit 75D, isoform A) (Myosin phosphatase targeting subunit 75D, isoform C) (Myosin phosphatase targeting subunit 75D, isoform D)
Gene: MYPT-75D

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	17007873
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007476 - imaginal disc-derived wing morphogenesis GO:0017018 - myosin phosphatase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Dm			1 741
+	Dm
		1249016 Q8T0U6_DROME (18-330): 0: 579: 99.68		Q8SY34_DROME (1-741): 9.93e-132: 409: 100.00
+	Dm
		819272 PP1B_DROME (1-330): 0: 592: 100.00		Q86R99_DROME (43-547): 7.98e-91: 303: 28.19
+	Hs
		906572 PP1B_HUMAN (1-329): 0: 581: 88.75		PP16B_HUMAN (24-535): 2.18e-90: 296: 36.40
+	Hs
		225133 PP1B_HUMAN (1-329): 0: 581: 88.75		MYPT2_HUMAN (40-390): 1.1e-85: 293: 34.09
+	Hs
		737999 PP1G_HUMAN (1-330): 0: 572: 82.48		PP16B_HUMAN (24-535): 2.18e-90: 296: 36.40
+	Hs
		225129 PP1G_HUMAN (1-330): 0: 572: 82.48		MYPT2_HUMAN (40-390): 1.1e-85: 293: 34.09
+	Hs
		906561 PP1B_HUMAN (1-329): 0: 581: 88.75		PP16A_HUMAN (24-542): 2.14e-86: 284: 38.29
+	Hs
		161348 PP1B_HUMAN (1-329): 0: 581: 88.75		MYPT1_HUMAN (110-488): 1.76e-81: 282: 29.43
+	Gg
		907234 PP1B_CHICK (1-329): 0: 581: 88.75		MYPT1_CHICK (117-488): 1.12e-81: 282: 31.90
+	Hs
		737978 PP1G_HUMAN (1-330): 0: 572: 82.48		PP16A_HUMAN (24-542): 2.14e-86: 284: 38.29
+	Hs
		161322 PP1G_HUMAN (1-330): 0: 572: 82.48		MYPT1_HUMAN (110-488): 1.76e-81: 282: 29.43
+	Dm
		1249926 Q8T0U6_DROME (18-330): 0: 579: 99.68		Q9VUX6_DROME (43-537): 8e-80: 274: 28.57
+	Mm
		926555 PP1G_MOUSE (1-330): 0: 572: 82.48		MYPT1_MOUSE (110-429): 2.44e-80: 279: 33.33
+	Hs
		906585 PP1B_HUMAN (1-329): 0: 581: 88.75		PP12C_HUMAN (110-491): 6.77e-73: 254: 27.27
+	Hs
		738024 PP1G_HUMAN (1-330): 0: 572: 82.48		PP12C_HUMAN (110-491): 6.77e-73: 254: 27.27
+	Dm
		115663 PP1B_DROME (1-330): 0: 592: 100.00		M9PFV2_DROME (213-741): 3.4e-55: 202: 23.39
+	Hs
		737925 PP1G_HUMAN (1-330): 0: 572: 82.48		ANR42_HUMAN (126-354): 3.63e-19: 92.4: 28.63
+	Hs
		906517 PP1B_HUMAN (1-329): 0: 581: 88.75		PPR27_HUMAN (113-228): 1.13e-17: 82.4: 34.19
+	Mm
		906252 PP1A_MOUSE (1-326): 0: 570: 82.42		PP12C_MOUSE (36-276): 4.49e-18: 91.1: 19.79
+	Hs
		3260 PP1B_HUMAN (1-329): 0: 581: 88.75		A0A0S2Z4Q8_HUMAN (262-368): 1.37e-11: 65.9: 33.33