HitPredict

Interactor 1: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Interactor 2: KP58 (Q9VPC0)
Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22) (Cell division cycle 2-like)
Gene: Pitslre

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21447707, 25294943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 330 Dm			1 952
+	Dm
		1249920 Q8T0U6_DROME (18-330): 0: 579: 99.68		KP58_DROME (1-952): 0: 648: 100.00
+	Hs
		625300 PP1B_HUMAN (1-329): 0: 581: 88.75		CDK2_HUMAN (555-863): 3.02e-145: 435: 43.69
+	Hs
		625180 PP1G_HUMAN (1-330): 0: 572: 82.48		CDK2_HUMAN (555-863): 3.02e-145: 435: 43.69
+	Hs
		738087 PP1G_HUMAN (1-330): 0: 572: 82.48		CDK12_HUMAN (15-908): 2.45e-132: 435: 20.24
+	Hs
		625299 PP1A_HUMAN (1-326): 0: 570: 82.73		CDK2_HUMAN (555-863): 3.02e-145: 435: 43.69
+	Sp
		532285 PP11_SCHPO (1-327): 0: 564: 77.37		POM1_SCHPO (4-946): 1.29e-134: 433: 15.16
+	Hs
		166547 PP1A_HUMAN (1-326): 0: 570: 82.73		DCLK1_HUMAN (117-938): 2.52e-134: 422: 15.91
+	Mm
		926533 PP1G_MOUSE (1-330): 0: 572: 82.48		CDK2_MOUSE (555-863): 1.04e-135: 412: 38.10
+	Hs
		414790 PP1G_HUMAN (1-330): 0: 572: 82.48		CDK1_HUMAN (555-854): 1.77e-133: 404: 42.33
+	Hs
		414846 PP1A_HUMAN (1-326): 0: 570: 82.73		CDK1_HUMAN (555-854): 1.77e-133: 404: 42.33
+	Mm
		509478 PP1G_MOUSE (1-330): 0: 572: 82.48		CDK1_MOUSE (555-854): 2.98e-132: 401: 42.67
+	Hs
		905833 PP1A_HUMAN (1-326): 0: 570: 82.73		CDK5_HUMAN (555-857): 8.43e-132: 400: 41.12
+	Hs
		625340 PP2AA_HUMAN (4-303): 3.18e-177: 494: 46.18		CDK2_HUMAN (555-863): 3.02e-145: 435: 43.69
+	Sp
		383446 PP11_SCHPO (1-327): 0: 564: 77.37		CDK1_SCHPO (555-854): 3.99e-70: 236: 43.23
+	Dm
		524602 PP12_DROME (1-303): 0: 548: 85.48		CDK2_DROME (555-861): 1.34e-74: 249: 42.17