HitPredict

Interactor 1: RAC2 (P48554)
Ras-related protein Rac2
Gene: RAC2

Interactor 2: Q7YZA0 (Q7YZA0)
Trio, isoform B (Trio, isoform F)
Gene: trio

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	10847683, 19176590
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGEF
Common GO terms	GO:0030036 - actin cytoskeleton organization GO:0050770 - regulation of axonogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 658
+	Hs
		500934 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		MCF2_HUMAN (267-656): 5.15e-88: 296: 25.19
+	Hs
		925405 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		ARHGP_HUMAN (262-658): 6.58e-91: 295: 31.30
+	Hs
		925649 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		ARHG4_HUMAN (116-658): 2e-89: 294: 14.02
+	Hs
		166482 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		MCF2L_HUMAN (247-644): 3.73e-85: 291: 24.46
+	Hs
		506566 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		BCR_HUMAN (27-608): 2.02e-80: 279: 14.83
+	Hs
		564737 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		PKHG1_HUMAN (235-643): 5.71e-79: 275: 21.23
+	Mm
		925798 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		BCR_MOUSE (71-608): 1.69e-79: 276: 14.62
+	Hs
		925727 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PKHG1_HUMAN (235-643): 5.71e-79: 275: 21.23
+	Hs
		925382 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PREX2_HUMAN (315-645): 1.18e-77: 272: 20.27
+	Hs
		925455 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PREX1_HUMAN (288-645): 4.56e-77: 270: 20.75
+	Hs
		548678 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		VAV_HUMAN (271-641): 8.94e-77: 264: 16.88
+	Hs
		925622 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PKHG2_HUMAN (335-643): 2.41e-74: 262: 24.70
+	Hs
		925330 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PKHG4_HUMAN (182-642): 2.69e-74: 261: 21.62
+	Hs
		50555 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		PKHG3_HUMAN (244-643): 2.93e-73: 258: 21.10
+	Hs
		50580 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PKHG3_HUMAN (244-643): 2.93e-73: 258: 21.10
+	Hs
		925527 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		SPT13_HUMAN (294-654): 1.04e-75: 257: 18.78
+	Ce
		975576 RAC1_CAEEL (1-192): 1.93e-82: 244: 79.69		Q7KPP4_CAEEL (281-638): 4.98e-72: 256: 24.15
+	Hs
		279854 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		TRIO_HUMAN (309-642): 7.08e-69: 247: 29.12
+	Hs
		224711 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		KALRN_HUMAN (309-642): 8.79e-69: 246: 28.82
+	Dm
		71592 RAC1_DROME (1-192): 2.59e-81: 241: 93.23		B3DN64_DROME (322-598): 2.02e-12: 72.8: 23.02