Interactor 1: HOSC (P48570)
Homocitrate synthase, cytosolic isozyme (HCS) (EC 2.3.3.14)
Gene: LYS20

Interactor 2: HOSM (Q12122)
Homocitrate synthase, mitochondrial (HCS) (EC 2.3.3.14)
Gene: LYS21

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 16554755, 18467557, 37968396, 22615397
Identification Methods affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HMGL-like~HMGL-like
Common GO terms GO:0004410 - homocitrate synthase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0019878 - lysine biosynthetic process via aminoadipic acid
GO:0046872 - metal ion binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 428
Sc

1 440
+ Sc
+ Sc
+ Sp
+ Ss
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024