Protein: DIA2
Protein DIA2 (Digs into agar protein 2)

Gene: DIA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: Q08496

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0001403 - invasive growth in response to glucose limitation
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0006275 - regulation of DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

910799

SKP1
Suppressor of kinetochore protein 1

7

0

Small-scale

0.913

High

1064364

CDC53
Cell division control protein 53

5

0

Small-scale

0.871

High

1030407

CTF4
DNA polymerase alpha-binding protein

7

0

Small-scale

0.722

High

794102

MCM7
DNA replication licensing factor MCM7

5

1

Small-scale

0.718

High

677709

MRC1
Mediator of replication checkpoint protein 1

4

0

Small-scale

0.681

High

713046

MCM2
DNA replication licensing factor MCM2

3

3

Small-scale

0.679

High

1042684

SLD5
DNA replication complex GINS protein SLD5

3

0

Small-scale

0.613

High

664473

MCM3
DNA replication licensing factor MCM3

2

3

Small-scale

0.611

High

713312

MCM5
Minichromosome maintenance protein 5

2

3

Small-scale

0.611

High

804521

SSZ1
Ribosome-associated complex subunit SSZ1

2

1

High-throughput

0.601

High

676424

MAS5
Mitochondrial protein import protein MAS5

2

1

High-throughput

0.584

High

1061502

CDC45
Cell division control protein 45

2

0

Small-scale

0.547

High

546562

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.536

High

574614

YAK1
Dual specificity protein kinase YAK1

1

0

High-throughput

0.513

High

633275

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

High-throughput

0.513

High

677251

SPB1
27S pre-rRNA

1

0

High-throughput

0.513

High

758266

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.513

High

798341

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.513

High

806179

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.513

High

807165

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

1027292

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.513

High

1064361

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.513

High

1064362

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.513

High

1064371

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

1064372

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.513

High

804679

SSF1
Ribosome biogenesis protein SSF1

1

1

High-throughput

0.489

High

1064366

SSF2
Ribosome biogenesis protein SSF2

1

1

High-throughput

0.489

High

550701

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.480

High

1062879

RBX1
RING-box protein HRT1

1

0

Small-scale

0.480

High

403680

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.479

High

645553

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

801943

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.479

High

721424

MCM4
DNA replication licensing factor MCM4

1

4

Small-scale

0.479

High

917072

MCM6
DNA replication licensing factor MCM6

1

3

Small-scale

0.479

High

1064367

YRA1
RNA annealing protein YRA1

1

1

Small-scale

0.479

High

479283

CDC6
Cell division control protein 6

1

0

Small-scale

0.458

High

763300

SGS1
ATP-dependent helicase SGS1

1

0

Small-scale

0.458

High

805847

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

823321

PSF2
DNA replication complex GINS protein PSF2

1

0

Small-scale

0.458

High

863241

DPOD2
DNA polymerase delta small subunit

1

0

Small-scale

0.458

High

1042255

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

Small-scale

0.458

High

1047269

CSM3
Chromosome segregation in meiosis protein 3

1

0

Small-scale

0.458

High

1064365

PSF3
DNA replication complex GINS protein PSF3

1

0

Small-scale

0.458

High

1064370

PSF1
DNA replication complex GINS protein PSF1

1

0

Small-scale

0.458

High

1062750

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.457

High

1064363

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.457

High

481793

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

525390

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

527880

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

671199

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

742563

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

819996

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

863993

JJJ2
J protein JJJ2

1

1

High-throughput

0.445

High

925108

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

393460

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

653911

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

912464

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

811056

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

826507

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.407

High

865093

TCPQ
T-complex protein 1 subunit theta

2

0

High-throughput

0.305

High

481919

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

758185

LST4
Protein LST4

1

0

High-throughput

0.279

Low

794734

SEA4
SEH-associated protein 4

1

0

High-throughput

0.279

Low

802598

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

803958

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.279

Low

843283

KRI1
Protein KRI1

1

0

High-throughput

0.279

Low

844649

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.279

Low

916432

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.279

Low

924653

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.279

Low

1040606

COFI
Cofilin

1

0

High-throughput

0.279

Low

1062344

NOP12
Nucleolar protein 12

1

0

High-throughput

0.279

Low

1064369

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.279

Low

644850

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

836932

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

926288

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.261

Low

510873

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

577232

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

752827

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

810915

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

871575

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

1046757

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

1064368

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025