Interactor 1: GCH1 (P48596)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) (Protein punch)
Gene: Pu

Interactor 2: GCH1 (P48596)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) (Protein punch)
Gene: Pu

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 37061542, unassigned1513, 14605208
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_cyclohydroI~GTP_cyclohydroI
Common GO terms GO:0003934 - GTP cyclohydrolase I activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0006728 - pteridine biosynthetic process
GO:0006729 - tetrahydrobiopterin biosynthetic process
and 9 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 324
Dm

1 324
+ Rn
+ Hs
+ Ce
+ Sc
+ Hp
+ Ec
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024