HitPredict

Interactor 1: GID8 (P40208)
GID complex subunit 8 (Dosage-dependent cell cycle regulator 1) (Glucose-induced degradation protein 8)
Gene: GID8

Interactor 2: RMD5 (Q12508)
E3 ubiquitin-protein ligase RMD5 (EC 2.3.2.27) (GID complex catalytic subunit 2) (Glucose-induced degradation protein 2) (Required for meiotic nuclear division protein 5) (Sporulation protein RMD5)
Gene: RMD5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 16554755, 16872538, 35437932, 35650207, 37968396, 22645139
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CTLH~CTLH
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0034657 - GID complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045721 - negative regulation of gluconeogenesis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 455
Sc

1 421
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025